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Mesenchymal Stem Cells
as Therapeutics
Biju Parekkadan1,∗ and Jack M. Milwid1,2,∗
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o. 1Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital,
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w Shriners Hospital for Children, and Harvard Medical School, Boston, Massachusetts 02114;
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a y Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of
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n n Technology, Cambridge, Massachusetts 02139
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n i Annu. Rev. Biomed. Eng. 2010. 12:87–117 Key Words
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d v First published online as a Review in Advance on
e i mesenchymal stem cell, immunotherapy, clinical trials, paracrine,
m n April 20, 2010
U
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i y extracorporeal bioreactor, conditioned medium
B b
. The Annual Review of Biomedical Engineering is
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