Real time three dimensional single particle tracking spectroscopy for complex systems英文文献.pdfVIP

374 Laser Photon. Rev. 3, No. 4, 374–385 (2010) / DOI 10.1002/lpor.200910012 Abstract Complex systems are characterized by dynamical processes spread over multiple time and length scales. At a given instant, these systems can display spatial heterogeneities in which the local physical and chemical properties are nonuni- form, depending on the location. They can also exhibit dynami- cal heterogeneities in which the local dynamical characteristics vary with time. These types of systems pose unique experimen- tal challenges for their characterization and test of theoretical ideas. Recently, real-time three-dimensional (3D) single-particle tracking spectroscopy has been developed to address these kinds of problems. With this approach, in principle, one can follow how a system evolves spatially as well as temporally. This ar- ticle attempts to provide an introduction to this promising new technique by discussing the aims of studying a complex system Cartoon illustrating a complex system, whose dynamics change and recent experimental advances towards this goal. as a function of time and position, studied using 3D particle- tracking spectroscopy. © 2010 by WILEY-VCH Verlag GmbH Co. KGaA, Weinheim Real-time three-dimensional single-particle tracking spectroscopy for complex systems * Daniel Montiel and Haw Yang Department of Chemistry, the University of California at Berkeley Physical Biosciences Division, Lawrence Berkeley National Laboratory Berkeley, CA 94720, USA Received: 12 February 2009, Revised: 26 March 2009, Accepted: 31 March 2009 Published online: 2 June 2009 Key words: Single-molecule sp