AP Bio Lab #8 Population Genetics and Evolution：AP生物实验室# 8群体遗传学和进化.docVIP

AP Bio Lab #8: Population Genetics and Evolution 8A: Phenotype Proportions of Tasters vs. Non-tasters (all classes) Phenotypes Allele Frequency Based on the Hardy-Weinberg Equation Tasters Non-tasters All Classes Combined as One Population # % # % p q 33 0.42 46 0.58 North American Population 0.55 0.45 Show work: 8B: Case Studies CASE I: Hardy-Weinberg Equilibrium Theoretical Initial Class Frequencies: AA: 0.25 Aa: 0.50 aa: 0.25 p: 0.5 q: 0.5 Class Pooled Data ( all classes): n = 68 (note that n might vary for other Cases below because different numbers of students were out of class on the different days this lab was run). Generation Class Totals for each Genotype AA Aa aa F1 21 33 14 F2 16 41 11 F3 25 28 15 F4 21 35 12 F5 31 29 8 Since the initial population consisted of all heterozygotes for simplicity, you cannot calculate the allele frequencies by taking the square roots of q2 and p2. This is because such a population is NOT in Hardy-Weinberg equilibrium. Calculate the allele frequencies as follows: Allele Frequency: The allele frequencies, p and q, should be calculated for the population after five generations of simulated random mating. Number of A alleles present at the fifth generation Number of offspring with genotype AA __________X 2 = _______________ A alleles Number of offspring with genotype Aa __________X 1 = _______________ A alleles Total = _______________ A alleles Number of a alleles present at the fifth generation Number of offspring with genotype aa __________X 2 = _______________ a alleles Number of offspring with genotype Aa __________X 1 = _______________ a alleles Total = _______________ a alleles Final Class Frequencies (after five generations = F5): AA: ___ Aa: ___ aa: ___ p: ___ q: ___ CASE II: Selection Theoretical Initial Class Frequencies: AA: 0.25 Aa: 0.50 aa: 0.25 p: 0.5 q: 0.5 Class Pooled Data (all classes): n = 68 (note tha