[临床医学]抗菌药物临床合理使用WXD20110316-1远程.pptVIP

不合理使用原因 不合理原因 病例数 百分率 围术期预防使用 10 52.6% 超适应症使用 4 21.1％ 细菌对同类药耐药 3 15.8％ 无感染出院带药 2 10.5% 氟喹诺酮类药使用合理性PDCA 预　祝 贵院在等级医院审评中 取得理想成绩！！ 王选锭 答案就在于MDR，也就是非发酵菌产生了多重耐药。 * * * For drugs where the kill rate is highly dependent on concentration, such as HMR 3647 and azithromycin, AUC/MIC is generally considered the best predictor of efficacy. For b-lactam antibiotics and the macrolides erythromycin and clarithromycin, the kill rate is not highly concentration-dependent, and so time over MIC is the best predictor of in vivo efficacy. For b-lactams, animal and clinical studies show that outcome depends on tim