Synthesis of Disubstituted Butenolides Based on a Pd…基于的双取代丁烯酰内酯的合成.pdfVIP

Synthesis of 5,5-Disubstituted Butenolides Based on a Pd- Catalyzed -Arylation Strategy The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. Citation Hyde, Alan M., and Stephen L. Buchwald. “Synthesis of 5,5- Disubstituted Butenolides Based on a Pd-Catalyzed -Arylation Strategy.” Organic Letters 11, no. 12 (June 18, 2009): 2663- 2666. As Published /10.1021/ol9007102 Publisher American Chemical Society (ACS) Version Authors final manuscript Accessed Tue Feb 23 23:37:49 EST 2016 Citable Link /1721.1/82106 Terms of Use Article is made available in accordance with the publishers policy and may be subject to US copyright law. Please refer to the publishers site for terms of use. Detailed Terms NIH Public Access Author Manuscript Org Lett. Author manuscript; available in PMC 2010 June 18. N Published in final edited form as: I H Org Lett. 2009 June 18; 11(12): 2663–2666. doi:10.1021/ol9007102. - P A A u Synthesis of 5,5-Disubstituted Butenolides Based on a Pd- t h o r Catalyzed ©-Arylation Strategy M a n * u Alan M. Hyde and Stephen L. Buchwald s c Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139 r i p t Abstract N I H - P A A u Methods for the construction of quaternary carbon centers are of great interest to synthetic chemists t h o due to their presence in natural products. Development of the P