注射用喜炎平药效学研究-1[WWW.WENDANGXIAZAI.COM].docVIP

时间就是金钱，效率就是生命！ 唯有惜时才能成功，唯有努力方可成就！ 　　 本文档下载自HYPERLINK /文档下载网，内容可能不完整，您可以点击以下网址继续阅读或下载： HYPERLINK /b-76193a6c25c52cc58bd6be6f.html/b-76193a6c25c52cc58bd6be6f.html 注射用喜炎平药效学研究 第11卷 第7期 2009 年 7 月 辽宁中医药大学学报 JOURNAL OF LIAONING UNIVERSITY OF TCM Vol. 11 No. 7 Jul .，2009 注射用喜炎平药效学研究 余 洋1，丛 艳2，权晓丹2，魏 晶1 （1.辽宁省食品药品检验所，辽宁 沈阳 110023；黑龙江 哈尔滨 150090）2.哈尔滨三元阳普医药科技有限公司，摘 要：目的：研究注射用喜炎平的药理作用。方法：进行了体内抗菌试验，解热试验，抗炎试验及止咳试 验。结果：注射用喜炎平对金黄色葡萄球菌、肺炎链球菌感染小鼠有明显的保护作用，其ED50分别为389.2mg/kg、475.9mg/kg；有明显的解热、抗炎作用；对枸橼酸致豚鼠咳嗽次数有明显抑制作用。结论：注射用喜炎平具有清热解毒，抗菌消炎，止咳的药理作用。 关键词：注射用喜炎平；药效学；清热解毒；抗菌消炎；止咳 (2009)07- 中图分类号：R285.5 文献标识码：A 文章编号：1673-842X 0198- 03Pharmacodynamics Studies of XiYanPing for Injection CONG Yan2，QUAN Xiao-dan2，WEI Jing1YU Yang1， （1.Liaoning Provincial Institute Control of Food and Drug Products，Shenyang 110023，Liaoning,China；2.Harbin Three Yang Pu Medicine Science and Technology Company Limited，Harbin 150090,Heilongjiang,China） Objective:To investigate the pharmacologic action of XiYanPing for injection.Methods:We Abstract： Results:s/b-76193a6c25c52cc58bd6be6f.htmltudied the antibacterial in vivo test, fever-relieving test, anti-inflammatory test and antitussive test. XiYanPing for injection had remarkable effect on mice infected by SA and SP,and the ED50s of it given by i.v were 389.2mg/kg,475.9mg/kg respectively;It had significantly anti-inflammatory effects and fever-relieving effects.XiYanPing for injection had obvious antitussive effect guinea-pig cough induced by citric acid，becouse it can reduced the frequence of cough.Conclusions:XiYanPing for injection has remarkable effects of clearing heat and toxic,antibacterial and anti-inflammation, antitussive. Key words：XiYanPing injection;Pharmacodynamics;clearing heat and toxic;antibacterial and anti-inflammatory;antitussive 注射用喜炎平是一种新型中药制剂，是从蕨类 植物穿心莲中提取制成水溶性穿心莲总内酯磺化物，具有清热解毒，抗菌消炎，止咳的药理作用。本 [1] 文研究了注射用喜炎平静脉注射给药对金黄色葡萄球菌、肺炎链球菌感染小鼠的保护作用试验；对内毒素所致家兔发热的解热作用试验；对醋酸所致的小鼠腹腔毛细血管通透性增高的影响试验；对枸橼酸/b-76193a6c25c52cc58bd6be6f.html致豚鼠咳嗽