(精选)PRINCIPLES OF HEMODYNAMICS教学课件.pptVIP

ACUTE INFLAMMATION INCREASED VASCULAR PERMEABILITY Normal flow Stasis ACUTE INFLAMMATION HEMOCONCENTRATION AND STASIS ACUTE INFLAMMATION LEUKOCYTE ADHESION ACUTE INFLAMMATION LEUKOCYTE ADHESION Fat Air Bone marrow Tumor Amniotic fluid Foreign body EMBOLIZATION NON-THROMBOTIC FAT EMBOLIZATION /WebPath FAT EMBOLIZATION /WebPath FAT EMBOLIZATION /WebPath AMNIOTIC FLUID EMBOLIZATION SHOCK Hypovolemic Cardiogenic Vascular Neurogenic Septic Anaphylactic DECREASED PERFUSION OF BODY TISSUES SHOCK SHOCK Reduced blood volume Decreased blood return to the heart Decreased cardiac output Decreased blood flow Tissue hypoxia Lactic acidosis Vasodilation and Increased vascular permeability Peripheral pooling and fluid loss into tissues SHOCK Cerebral neuronal necrosis Acute renal tubular necrosis (ATN) Centrilobular hepatic necrosis Gastrointestinal mucosal necrosis Diffuse alveolar damage EFFECTS ON TISSUE SHOCK CLINICAL SEQUELAE SHOCK Tachycardia Ineffective blood volume Cool, clammy skin Warm, moist skin Oliguria Metabolic acidosis PRINCIPLES OF HOST DEFENSE Intensity Time Neutrophils Lymphocytes Macrophages Fibroblasts Fibrosis Acute Chronic Scar HOST DEFENSE INJURY REPAIR HOST DEFENSE HOST DEFENSE HOST DEFENSE POLYMORPHONUCLEAR LEUKOCYTES Neutrophils Eosinophils Basophils CELLULAR PARTICIPANTS POLYMORPHONUCLEAR LEUKOCYTES Neutrophil Eosinophil Basophil MAST CELLS HOST DEFENSE MONONUCLEAR LEUKOCYTES Lymphocytes Monocytes CELLULAR PARTICIPANTS MONONUCLEAR LEUKOCYTES LYMPHOCYTES MONONUCLEAR LEUKOCYTES MONOCYTE / HISTIOCYTE/ MACROPHAGE PLATELETS Intensity Time Neutrophils Lymphocytes Macrophages Fibroblasts Fibrosis Acute Chronic Scar HOST DEFENSE ACUTE INFLAMMATION ACUTE INFLAMMATION INJURY Acute inflammation Mediators ACUTE INFLAMMATION ACUTE INFLAMMATION Vasoconstriction Vasodilation Increased vascular permeability Hemoconcentration and stasis Leukocyte Adhesion Transmigration Chemotaxis Aggregation Phagocytosis ACUTE INFLAMMATION SEQUENCE OF EVENTS ACUTE INFLAMMATION VA