(精编)【医学课件】Emodin azide methyl anthraquinone derivative induces proteasomal degradation of Her2neu in Her2neu-overexpressing cancer cells教学课件.pptVIP

中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER Emodin azide methyl anthraquinone derivative induces proteasomal degradation of Her2/neu in Her2/neu-overexpressing cancer cells Li-sheng Zheng, Yan-yan Yan, Li-wu Fu Cancer Center, Sun Yat-sen University 2010. 5 ? Overexpression of HER2/neu is common in multiple malignancies, including breast, ovarian, lung and prostate cancer, etc. ? Clinical studies have demonstrated that elevated HER2/neu expression correlates with poor prognosis in multiple malignancies ? During the last decade, HER2/neu has been targeted in order to