Current Ethical Issues in Neuroimaging - Bioethics目前神经影像的生命伦理学中的伦理问题.pptVIP

Current Ethical Issues in Neuroimaging Adina Roskies Dartmouth College Presentation to the Presidential Commission for the Study of Bioethical Issues, February 28, 2011 Neuroimaging Primarily diagnostic, descriptive/predictive, non-interventional Can be used in conjunction with interventional techniques like TMS, DBS which raise other ethical issues “We are our brains” more immediate than “We are our genes” Parallels with HGP ELSI Many similar informational risks Some differences: potential to pose a different kind of privacy threat consent issues usually the information does not affect people other than subject neurological cases often involve competence Privacy/potential forensic uses of neuroimaging Mental Content MVPA allows prediction of visual content on basis of brain data (Mitchell et al, 2008, Shinkareva et al. 2008, Just et al. 2010) Lie/truth detection knowledge/familiarity measures of arousal measures of subjective but not objective familiarity (Rissman, Greely Wagner, 2010) pain Mental Privacy, Lie detection Techniques for assessing these better than chance, but: experimental design problems experimental confounds unknown base rates (prevalence in the relevant population) are apt to be misleading All these provide only probabilistic information Prediction Prediction of brain disease Potential forensic uses of predictive neuroimaging Aggression/Antisocial behavior Recidivism Mental illness Probabilistic information, no definitive predictions can currently be made In many cases, we don’t know baserates The ethics of consciousness Recent developments in understanding/diagnosing disorders of consciousness Mental imagery (Owen et al., 2006, Monti et al. 2010) Trace conditioning (Bekinschtein et al., 2009) Ethical implications of these developments for extending life, pain management, quality of life considerations Underlying importance of considerations of welfare and autonomy Responsibility and culpability Biological picture puts pressure on commonse