2007 2009年icu医院感染状况调查与分析 word格式.docxVIP

摘要2007～2009年ICU医院感染状况调查与分析研究生：张先玲导师： 于湘友 副教授摘要目的：回顾调查分析 ICU 内医院获得性感染(Nosocomial Infection, NI) 的流行病 学规律、病原体、医院感染类型和分布，为 ICU 医院感染的防治提供依据。方法： 收集整理 2007 年 1 月～2009 年 12 月入住 ICU 的 7738 份，符合医院感染诊断标准的临床资料进行统计分析。同时按标准剔除部分病例。筛选出 427 例病例进行回顾 性分析。通过查阅病史及医院感染登记表后统一填写调查表。调查内容主要包括性 别、年龄、原发病、住院天数、感染日期、易感因素、侵入性操作、抗生素使用情 况、感染部位、致病菌及药敏。对上述数据进行统计学分析。结果：2007～2009 年 ICU 医院感染感染人次率 5.52%，感染例次率为 15.3%，3 年感染率比较具有统计学 差异。常见感染部位依次是呼吸道、血液、术区引流、切口、中心静脉导管、泌尿 系统、颅内、胸膜腔等，感染构成比分别为 72.1%、9.4%、4.7%、2.7%、2.1%、1.4%、 1.2%、1.2%，ICU 医院获得性感染病原菌的排名依次是鲍曼不动杆菌、金黄色葡萄 球菌、铜绿假单胞菌和肺炎克雷伯菌。结论：ICU 内医院感染的患病率仍居高不下， 应采取综合措施，加强医院感染防治，从而降低 ICU 感染率。关键词：医院感染；重症监护病房；革兰阴性杆菌；革兰阳性球菌；真菌新疆医科大学医学硕士学位论文Retrospective investigation and analysis of nosocomial infections in the Intensive Care Unit during 2007～2009Postgraduate:Zhang Xian-lingSupervisor: Yu Xiang-you Associate ProfessorAbstractObjective: To analyze the prevalence of nosocomial infection(NI)，the type and distribution of pathogens，and provide evidence for infection prevention and treatment.Methods: There were 7738 cases in intensive care unit (ICU) from Jan. 2007 to Dec. 2009. Among these cases 427 paients were NI according to the diagnostic criteria and others were eliminated. Then fill in the unity questionnaire and registrated schedule of NI. The date mainly include gender, age, stay in hospital, date of infection, sites of infection, predisposing factor, invasive operation, information of using antibiotics, pathogenic bacterium and drug sensitivity. Then analyse these date. Results: The average the prevalence of NI was 5.52 %. The number nosocomial infection patients were 427, and the rate is 5.52%, the incidence of infection was 15.3%. There are significant difference in the three years. The major infected sites of NI is respiratory tract (72.1%), bloodstream infections (9.4%), operated drainage(4.7%), operated cut (2.7%), central venous catheter(2.1%),urinary tract (1.4%), cerebrospinal fluid(1.2%), pleural cavity(1.2%). The most common pathogens of NI were Baumanii,