不同调制频率对听性稳态反应阈值的影响-耳鼻咽喉科学专业论文 word格式.docxVIP

优秀毕业论文 精品参考文献资料 PART Ⅱ：ASSR examination in different modulation frequencies of normal guinea pigs Objective: To investigate the influence in different modulation frequencies (MF) of the threshold of ASSR , and establish the best threshold of ASSR in normal guinea pigs. Methods: 12 guinea pigs (24 ears) with normal hearing sedated by pentobarbital sodium were selected to ASSR test. The equipment was Audera ASSR from American GSI. The test were performed in different modulation frequencies ,stimulus sounds were presented in monaural by the standard Tip-50 insert phones. ASSR parameters: carrier frequency (CF) are 0.5 、1、2、3、4、6 kHz, modulation frequency (MF) are 21、46、67、74、81、110、154 and 199 Hz. Results:When CF equaled to 0.5 kHz, the threshold of ASSR with MF of 154Hz was lower than other MF, had statistically significant differences (P 0.05) except for MF of 110 and 67Hz ;when CF was amount to 1 kHz, the threshold of ASSR with MF of 199Hz was lowest ,had significant differences to 21,46 and 81 Hz; In CF of 2 kHz, the minimum threshold of ASSR was in 154 Hz , had statistically differences (P0.05) to 21~74 Hz; In CF of 3 and 6 kHz, the lowest threshold of ASSR was in 199 Hz,compared to 21~81 Hz, there was statistically significant differences (P 0.05); When CF equaled to 4 kHz, there was statistically significant differences (P 0.05) compared to MF of 21~81 Hz. Conclusion:MF affect the thresholds of ASSR,in sedation, the threshold were higher in low modulation frequencies, and were lower in high modulation frequencies. The best MF of ASSR threshold would be between 154 Hz and 199 Hz. Key words: modulation frequency; auditory steady state response; guinea pigs 1 1 缩写 英文缩写 英文全称 中文全称 ABR auditory brainstem response 听性脑干反应 ASSR auditory steady state response 听性稳态反应 AM amplitude modulation 调幅 FM frequency modulation 调频 MM mixed modulation 混合调制 CF carrier frequency 载波频率 MF modulation frequency 调制频率 FFT fast fourier transform 快速傅立叶变换 PTA pure tone audiometry 纯音听阈 OAE otoac