雷帕霉素对tnbs诱导小鼠炎症性肠病的治疗作用及机制分析-病原生物学专业论文.docxVIP

目录摘要....................................................................................................................IAbstract...................................................................................................................III第一章 序言.............................................................................................................1第二章 雷帕霉素对炎症性肠病的治疗效果...........................................................42.1 前言.............................................................................................................42.2 实验材料.....................................................................................................42.2.1 主要实验材料....................................................................................42.2.2 主要试剂............................................................................................42.2.3 主要仪器设备....................................................................................42.2.4 主要溶液配制....................................................................................52.3 实验方法.....................................................................................................5TNBS诱导的IBD模型建立5RAPA给药治疗IBD52.3.3 肠组织HE 染色52.3.4结肠炎严重程度评估........................................................................72.4 实验结果.....................................................................................................82.4.1 体重变化结果....................................................................................82.4.2TNBS肠炎DAI评分92.4.3组织学观察与病理评分....................................................................92.5 讨论...........................................................................................................11第三章 雷帕霉素诱导的调节性T细胞的在治疗中的作用133.1 前言...........................................................................................................133.2 实验材料...................................................................................................133.2.1 主要实验材