补体的生理学病理学意义 知识介绍.pptVIP

?2001 免疫学信息网 补体(complement，C) 补体：是存在于人和脊椎动物血清与组织液中一组经活化后具有酶活性的蛋白质 Jules Bordet? (1870-1961), discoverer of complement Belgian bacteriologist and immunologist who received the Nobel Prize for Physiology or Medicine in 1919 for his discovery of immunity factors in blood serum; this was a development vital to the diagnosis and treatment of many dangerous contagious diseases. Components of the complement 1. 固有成分 Classical pathway：C1（C1q, C1r,C1s）, C4, C2, C3 MBL Pathway： MBL，MASP, C4, C2, C3 Alternative Pathway ：C3，Factor B，Factor D Terminal pathway: C5, C6, C7, C8, C9 2