可调脉宽倍频ndyag激光治疗皮肤血管性疾病的疗效及安全性观察-observation on efficacy and safety of adjustable pulse width doubled nd yag laser in the treatment of cutaneous vascular diseases.docxVIP
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可调脉宽倍频ndyag激光治疗皮肤血管性疾病的疗效及安全性观察-observation on efficacy and safety of adjustable pulse width doubled nd yag laser in the treatment of cutaneous vascular diseases
provisional hyperpigmentation.None of any cases formed scar.After 1-5 times oftreatment with variable pulse width frequency doubled Nd:YAG laser,24 cases of angiokeratoma were healed , the recovery rate was 100 %. No case developed hyperpigmentation,scar or infection.Two infants with cutanenous hemangioma in the perineal region have received satisfactory effect without any side effect. No recurrence occurred during a 6-month follow-up period.ConclusionA variable long-pulsed Nd: YAG laser was found to be effective and safe in the treatment of telangiectasis 、angiokeratoma and cutanenous hemangioma in the perineal region. The effect of telangiectasis was obvious after two times of treatment. Most patients reached recovery after three times.The effective rate and the recovery rate was as higher as more times,but there was no significant difference after 2、3 times by statistical treatment. The recovery rate of facial telangiectasis was higher than the nasal’s. This laser machine can be clinical applied widely in the treatment of telangiectasis and angiokeratoma.The authors have indicated no significant interest with commercial supporters.Key wordsvariable pulse width frequency doubled Nd:YAG laser;dermovascular disease; telangiectasis; angiokeratoma; cutanenous hemangioma in the perineal region学位论文原创性声明本论文是我个人在导师指导下进行的工作研究及取得的研究成果。论文 中除了特别加以标注和致谢的地方外,不包含其他人或其它机构已经发表或 撰写过的研究成果。对本文的研究做出贡献的个人和集体,均已在论文中以 明确方式标明。本人完全意识到本声明的法律责任由本人承担。作者签名:日期:年月日学位论文使用授权声明本人授权汕头大学保存本学位论文的电子和纸质文档,允许论文被查阅 和借阅;学校可将本学位论文的全部或部分内容编入有关数据库进行检索, 可以采用影印、缩印或其它复制手段保存和汇编论文;学校可以向国家有关 部门或机构送交论文并授权其保存、借阅或上网公布本学位论文的全部或部 分内容。对于保密的论文,按照保密的有关规定和程序处理。本论文属于:保密(),在年解密后适用本授权声明。 不保密()。(请在以上括号内打“√”)作者签名:导师签名: 日期:年月日日期:年月日第 1 章 前言皮肤血管性疾病是常见的损容性疾病,种类繁多。常见的有毛细血管扩张症、鲜红斑痣、草莓状血管瘤、海绵状血管瘤、血管角皮瘤等,其中鲜红斑痣发病率高达 0.3-0.5%【1】。 皮肤血管性疾病多不至于危及生命,但如发生于面部及其它暴露部位时,影响容貌,给患者精神心理、生活造成极大的影响。传统治疗方法有液氮冷冻治疗、核素敷贴、微波治疗、硬化剂注射治疗、口服激素、 手术切除等破坏性治疗,存在各种缺陷。在治疗皮肤血管性疾病的同时极易造成组织的瘢痕、色素沉着、疼痛及其它相关副作用,病人往往难以接受。上世纪60年代开始了激光治疗皮肤血管性疾病,相继有694nm红宝石激光、488nm氩离子激光治疗血管性
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