(耳鼻咽喉头颈外科学)（参考翻译）Laryngeal_CA宣讲培训.pptVIP

Laryngeal Cancer喉癌;Anatomy 解剖;Anatomy 解剖;Supraglottis 声门上 Glottis 声门 Subglottis 声门下;Anterior Commissure 前联合 False Cords 假声带 True Vocal Cords 声带 Trachea 器官 Arytenoids 甲状软骨;Lymphatic Drainage 淋巴引流;Lymphatic Drainage 淋巴引流;Most common head and neck cancer 12,250 new cases/yr(USA), 60,000 new cases/yr(CHN) Male : Female = 10 : 1 Age: 40－70 year 90-95% squamous cell cancer 鳞状细胞癌;各区域喉癌发生率;Tobacco smoking 吸烟 Alcohol abuse 酗酒 HPV infection HPV感染 Air pollution 空气污染 ;Clinical Presentation 临床表现 ;Supraglottic Cancer 声门上区癌;Supraglottic tumors more aggressive: Direct extension into pre-epiglottic space 直接蔓延至会厌前间隙 Lymph node metastasis 淋巴结转移 Direct extension into lateral hypopharnyx and tongue base 直接蔓延至侧咽及舌根 ;Glottic cancer 声门癌;Glottic tumors grow slower and tend to metastasize late. 声门肿瘤生长缓慢，转移较晚 They tend to metastasize after they have invaded adjacent structures with better drainage. 其倾向于转移至引流更好的毗邻结构 Can cause vocal cord fixation 可造成声带固定 ;Subglottic Cancer 声门下癌;Clinical Presentation 临床表现;Clinical Presentation 临床表现;Clinical Presentation 临床表现;Imaging 影像学;CT SCAN;Biopsy and Histology 组织活检;Diagnosis 诊断;Differential Diagnosis 鉴别诊断;TB 肉芽肿;Papillomatosis 乳头瘤;Polyps 息肉;Supraglottis Tis: CA in-situ T1: limited to subsite of supraglots w/normal cord mobility T2: invade mucosa of 1 subsite of supraglottis, glottis, or outside of supraglottis w/out fixation of the larynx T3: limited to larynx w/vocal cord fixation and/or invades postcricoid area, pre-epiglottic tissues, paraglottic space, and/or minor thyroid cartilage erosion T4a: invades thyroid cartilage and/or tissues beyond larynx T4b: invades prevertebral space, encases carotid artery, ;Supraglottis Tis: CA in-situ T1: limited to subsite of supraglots w/normal cord mobility T2: invade mucosa of 1 subsite of supraglottis, glottis, or outside of supraglottis w/out fixation of the larynx T3: limited to larynx w/vocal cord fixation and/or invades postcricoid area, pre-epiglottic tissues, paraglottic space, and/or minor thyroid car