前列地尔对非st段抬高型心肌梗死合并肾功能 不全pci患者的肾脏保护效应-renal protective effect of alprostadil on patients with non - st - segment elevation myocardial infarction complicated with renal insufficiency pci.docxVIP

目录中文摘要···········································································································1 英文摘要···········································································································4 英文缩写···········································································································8 研究论文 前列地尔对非 ST 段抬高型心肌梗死合并肾功能不全 PCI 患者的肾脏保护效应前言········································· ········ ······················································10 材料与方法·····························································································12 结果·········································································································16 附图·········································································································18 附表·········································································································20 讨论·········································································································23 结论·········································································································26 参考文献·································································································27 综述 对比剂肾病发病机制的研究进展·······················································30 致谢·················································································································40 个人简历·················································································· ······················41前列地尔对非 ST 段抬高型心肌梗死合并肾功能不全 PCI 患者的肾脏保护效应摘要目的：本研究旨在评价静脉应用前列地尔对非 ST 段抬高型心肌梗死（non-ST elevation myocardial infarction, NSTEMI）合并肾功能不全（renal insufficiency, RI ） 行 经 皮 冠 状 动 脉 介 入 治 疗 （ percutaneous coronary intervention, PCI）患者的肾脏保护效应。方法：本研究为前瞻、随机对照研究。入选 2014 年 12 月至 2015 年 12 月就诊于河北医科大学第二医院心内五科病房的符合非 ST 段抬高型 心肌梗死合并肾功能不全诊断标准的连续患者 120 例，将入选患者随机分 为前列地尔（PGE）组和对照（CON）组，其中 PGE 组 60 例，CON 组 60 例。入选标准：1) 符合非 ST 段抬高型心肌梗死的诊断标准；2) 符合 美国肾脏基金会制定的慢性肾脏病（chroni