异种生物型防粘连膜预防肌腱粘连的实验分析-experimental analysis on prevention of tendon adhesion with xenobiotic anti-adhesion membrane.docxVIP
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异种生物型防粘连膜预防肌腱粘连的实验分析-experimental analysis on prevention of tendon adhesion with xenobiotic anti-adhesion membrane
<0.05).Vitodynamicstest:Thetensilestrengthineachgroupissimilarity;theglidingdistanceandtheflexibleangulationofinterphalangealjointingroupAandgroupBisbiggerthangroupC(P<0.05).Histologytest:IngroupAandgroupB,tendoncellproliferationinthemain,afewcollagenoblastandcollagenfibersaroundtendon,andarrangeregularity,adherewithtendonsloppy,mostof1-2gradeinflammatoryresponse.IngroupC,collagenoblastandcollagenfibersproliferationinthemain,adherewithtendonclosely,therearealittleoftendoncells,anddisorderedarrange,mostof1-2gradeinflammatoryresponse.Amynologytest:ThevalueofCD4+andCD8+changelittleatdifferenttimepointsafteroperation,eachgroupissimilarity(P>0.05).Andatthesametime,groupAandgroupBincreaseserumIgGlevelishigherthangroupC,buttheydidnotreachthelevelincreaseby2times,socanbejudgedtobenegative,thatismeanthereisnosignificantdifferenceineachgroup.ConclusionHeterogeneousbiotypesmedicalfilmdoesnotcausesignificantcellualaandhumoralimmuneresponse,andhasgoodhistocompatibility.Heterogeneousbiotypesmedicalfilmcanbeeffectiveinpreventionoftendonadhesion,withoutaffectingtendonhealing.KeywordsHeterogeneous;MedicalFilm;TendonInjury;Repair;Adhesion.学位论文原创性声明本人郑重声明:所呈交的学位论文,是本人在导师的指导下,独立进行研究工作所取得的成果。文中依法引用他人的成果、对本文的研究作出重要贡献的个人和集体,均已在文中做出明确标注或得到许可。论文内容未包含法律意义上已属于他人的任何形式的研究成果,也不包含本人已用于其他学位申请的论文或成果。本人如违反上述声明,愿意承担以下责任和后果:1.交回学校授予的学位证书;2.学校可在相关媒体上对作者本人的行为进行通报;3.本人按照学校规定的方式,对因不当取得学位给学校造成的名誉损害,进行公开道歉。4.本人负责因论文成果不实产生的法律纠纷。论文作者签名:日期:年月日学位论文知识产权权属声明本人在导师指导下所完成的论文及相关的职务作品,知识产权归属广州医学院及附属单位。广州医学院及附属单位享有以任何方式发表、复制、公开阅览、借阅以及申请专利等权利。本人离校后发表或使用学位论文或与该论文直接相关的学术论文或成果时,署名单位仍然为广州医学院及附属单位。任何其他收存和保管本论文的单位和个人,未经本论文作者、导师授权,不得将本论文转借他人、复制、抄录或以其他任何方式传播,否则,引起有碍作者的著作权益问题,将会追究相应的法律责任。论文作者签名:日期:年月日导师签名:日期:年月日关于学位论文使用授权的说明1、学校可以保留本论文的原件及复印件和磁盘,允许论文被查阅和借阅,可以采用影印、缩印或扫描等复印手段保存、汇编学位论文;2、本人授权学校向国家有关部门或机构送交论文的复印件和电子版,允许论文被查阅和借阅。论文作者签名:日期:年月日导师签名:日期:年月日引言肌腱损伤、断裂在四肢创伤中极为常见,对其愈合形式及修复方法仍存在不少分歧。肌腱修复后长时间制动常常造成粘连,严重影响滑动功能,从而使肢体运动功能恢复不满意[1-2]。肌腱粘连常因需行二期松解术而增加患者的痛苦和经济负担。如何使肌腱在损伤后少发生或不发生粘连,尽快恢复其滑动功能,同时又不影响肌腱本身的愈合,是临床关注的焦点。许多学者致力于在肌腱和腱周组织之间建立一
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