抗生素精品课件Introductionfor .pptVIP

Introduction for Antibiotics  R3 孔祥琪Last revised: July 6, 2003Section of Infectious DiseasesDepartment of Internal Medicine National Taiwan University Hospital, Taipei 臨床上常見的致病微生物 Bacteria Viruses Fungi Mycobacterium Mycoplasma Protozoa 臨床上常見的致病菌 Aerobic Gram-positive bacteria Gram-negative bacteria Anaerobic Gram-positive bacteria Gram-negative bacteria Aerobic Gram-positive bacteria Cocci Staphylococcus spp. Streptococcus spp. Enterococcus spp. Bacilli Listeria spp. Bacillus spp. Staphylococci Coagulase-positive Staphylococcus aureus Coagulase-negative Staphylococcus epidermidis Staphylococcus saprophyticus Staphylococcus haemolyticus Methicillin-resistant MRSA MRCNS Methicillin-sensitive MSSA MSCNS Streptococci(1) Classification Lancefield: based on the antigenic characteristics of the outer membrane Brown: type of hemolysis Clinical: combines Lancefield, Brown, disease producing characterstics Streptococci(2) alpha hemolysisincomplete hemolysisS. viridans and S. pneumoniae beta hemolysiscomplete hemolysisGroup A Strep  = S. pyogenes Gamma hemolysisnonhemolyticSome Group D Strep. S. pyogenes (Group A, ? hemolytic) Pharyngitis Impetigo Viridans group (alpha hemolytic) Endocarditis S. pneumoniae (Pneumococcus) Bacteremia Pneumonia Meningitis Gram-positive bacilli Bacillus cereus Diptheroids Corynebacterium diptheriae JK group Corynebacterium Listeria monocytogenes Aerobic Gram-negative bacteria Bacilli Enterobacteriaceae NFGNB: Glucose Non-fermentative  Gram-negative bacilli Haemophilus species (H. influenzae; H. parainfluenzae) Legionella pneumophilia Cocci Neisseria gonorrhoeae (gonococcus) Neisseria meningitidis (meningococcus) Moraxella catarrhalis Gram-negative bacteria Enterobacteriaceae E. coli Klebsiella spp. Proteus spp. Salmonella spp. Shigella spp. Enterobacter spp. Citrobacter spp. Serratia spp. Edwardsiella spp. Yersinia spp. NFGNB Pseudomonas