血脂领域重大循证研究汇总ppt课件_1.ppt

Gould AL et al. Circulation. 1998;97:946-952.;PREMIER: Percentage of All Participants With Hypertension (6 mo)*;PREMIER: Percentage of All Participants With Optimal Blood Pressure (6 mo)*;Lp(a): An Independent CHD Risk Factor in Men of the Framingham Offspring Cohort;AFCAPS/TexCAPS: RR of Acute Coronary Events—LDL-C and Homocysteine*;AFCAPS/TexCAPS: RR of Acute Coronary Events—TC:HDL-C Ratio and CRP Level*;PRINCE: Change in CRP Levels at 24 Weeks; Non–HDL-C No. of Deaths (mg/dL) (Subjects) 160 60 (790) 160 to 190 56 (653) 190 to 220 53 (506) 3220 65 (432); Non–HDL-C No. of Deaths (mg/dL) (Subjects) 160 28 (898) 160 to 190 27 (465) 190 to 220 21 (337) 3220 37 (333);ACCESS: Change in LDL-C, Non–HDL-C in All Patients at 54 Weeks;PDAY: Percentage of Right Coronary Artery Intimal Surface Affected With Early Atherosclerosis;PDAY: Prevalence of Lesions in LAD;PDAY: Prevalence of Risk Factors;PDAY: Prevalence of Lesions by Smoking and Non–HDL-C Status;SHEEP: Risk Factors for Nonfatal MI in Men and Women;Elevated TC Effects on Risk of CHD Death in Younger Men: A Meta-analysis;NHANES I Epidemiologic Follow-up Study:CHD Incidence and Survival in African-American Men and Women;LDL-C target levels (mg/dL) 32 RF: 130 CHD: ￡100 National Center for Health Statistics. National Health and Nutrition Examination Survey (III); 1994. (Data collected 1991-1994.) Pearson TA et al. Arch Intern Med. 2000;160:459-467.;18;% of patients;L-TAP: Patient Success in Achieving Target LDL-C Levels;Adjusted* Relative Risk for First Cardiovascular Event Based on CRP, LDL-C;Event-Free Survival With CRP, LDL-C Levels Above or Below the Median*;Effects of Three Treatments on CRP;0;Lyon Diet Heart Study: Cumulative Survival Without Cardiac Death and Nonfatal MI;Wine Consumption and CHD;Effect of Lifestyle Changeson Angiographic CAD;-9;Early Secondary-Prevention Trials: Overview;-20;-20;5-year event rate (per 100);WOSCOPS: Relation of Baseline HDL-C to Event Rate;WOSCOPS: Relation Bet