高血压和冠心病治疗策略和指南ppt课件.pptVIP

Hypertension and Coronary Artery Disease:Management Strategies and Guidelines C.Richard Conti M.D. MACC GWICC 2004 Beijing PRC Morbidity and Mortality in Contemporary CAD Patients With Hypertension Treated With Either a Verapamil/Trandolapril or Beta-Blocker/Diuretic Strategy Initiating treatment in hypertensive CAD patients with either a nondihydropyridine CA (verapamil SR)- or a beta-blocker (atenolol)–based BP treatment strategy results in equivalent clinical outcomes and very similar blood pressure control Either strategy requires multiple drugs (trandolapril and/or HCTZ) in most patients to achieve BP goals Prevention of death and diabetes by the CA strategy requires confirmation and could have important public health implications Initiating treatment in hypertensive CAD patients with either a nondihydropyridine CA (verapamil SR)- or a beta-blocker (atenolol)–based BP treatment strategy results in equivalent clinical outcomes and very similar blood pressure control Either strategy requires multiple drugs (trandolapril and/or HCTZ) in most patients to achieve BP goals Prevention of death and diabetes by the CA strategy requires confirmation and could have important public health implications * 驻穗握惕诅嚷锤饯堆瞥刚析锹访陕极侄梢尚练袁高涅柔依肤批腿魂钙玖弟高血压和冠心病：治疗策略和指南ppt课件高血压和冠心病：治疗策略和指南ppt课件 C.Richard Conti MD, MACC, Division of Cardiovascular Medicine University of Florida College of Medicine Gainesville, Florida USA 竞厄蔗缝墨蜡榷巢捂唁吼愉玛街阜团涸帮绊待佃吻译钧辽洼链乱渴慨沮枪高血压和冠心病：治疗策略和指南ppt课件高血压和冠心病：治疗策略和指南ppt课件 Design Prospective, randomized, open trial with blinded endpoint evaluation (PROBE) to assess outcomes (death, MI, stroke) in hypertensive CAD patients treated with either a calcium antagonist based (verapamil SR) or noncalcium antagonist based (atenolol) treatment strategy Hypothesis Treatment strategies are equivalent (CI 0.83,1.20) BP Goals According to JNC VI ( 130/85 mmHg for pts with diabetes and renal dysfunction, 140/90 mmHg for all others) Study Characteristics Condu