义务教育11-2.pptVIP

Thus, malonic ester is easily converted into its enolate ion by reaction with sodium ethoxide in ethanol. Carbonyl condensation reactions, the fourth and last general category of carbonyl-group reactions well study involve both kinds of reactivity. These reactions take place between two carbonyl partners and involve a combination of nucleophilic addition and α-substitution steps. One partner (the nucleophilic donor) is converted into an enolate ion and undergoes an α-substitution reaction, while the other partner (the electrophilic acceptor) undergoes a nucleophilic addition reaction. Proble