吡哆胺对高糖“代谢记忆”致糖尿病视网膜病变的治疗作用-therapeutic effect of pyridoxamine on diabetic retinopathy caused by high glucose.docxVIP

目录英文缩写一览表…………………………………………………………………(3) 中文摘要…………………………………………………………………………(7) 英文摘要…………………………………………………………………………(9) 前言…………………………………………………………………………(12) 实验材料…………………………………………………………………………(16) 实验方法…………………………………………………………………………(19) 结果…………………………………………………………………………(28) 讨论…………………………………………………………………………(38) 结论…………………………………………………………………………(47) 参考文献…………………………………………………………………………(48) 致谢…………………………………………………………………………(57) 综述…………………………………………………………………………(58)2中英文缩略词表英文缩写AGEs英文全称advanced glycation end-products中文晚期糖基化终末产物AIAPP CEG CELapoptosis indexalkaline phosphatase Carboxylmethyl guanine Carboxyethyl lysine凋亡指数碱性磷酸酶 羧甲基鸟嘌呤 羧乙基赖氨酸CML CMV DCCTddH2O DMCarboxylmethyl lysine Carboxylmethyl valineDiabetes Control and Complications Trial double distilled H20diabetes mellitus羧甲基赖氨酸 羧甲基缬氨酸 糖尿病控制和并发症研究 双蒸水糖尿病DN DNA dNTP DR EDICdiabetic nephropathy deoxyribonucleic acid deoxyribonucleotide triphosphate diabetic retinopathyEpidemiology of Diabetes Interventions and糖尿病肾病 脱氧核糖核酸 脱氧核苷三磷酸 糖尿病视网膜病变糖尿病干预与并发症流行ELISAComplicationsenzyme-linked immunosorbent assay病学研究 酶联免疫吸附实验eNOSEP ETendothelial nitric oxide synthaseeppendorf tube early treatment内皮型一氧化氮合酶离心管 早期治疗GFAP HHE HRPICAM-1glial fibrillary acidic portein hourshematoxylin-eosin staining horseradish peroxidase intercellular adhesion molecule胶质纤维酸性蛋白 小时苏木精-伊红染色 辣根过氧化酶 细胞间黏附分子-1IL-1Interleukin-1白细胞介素-13ippIR MCP-1min MM MnSOD mRNA NADPHNCNF-κB NOOD PBS PCNA PCR PEDF PKC PM RAGERnase ROSRpm S SDSPSS STZ T1DM T2DMimageproplusinsuline receptormonocyte chemoattractant protein-1 minutesmetabolic memorymanganese superoxide dismutase messenger ribonucleic acidnicotinamide adenine dinucleotide phosphatenormal controlnuclear factor-Kappa B Nitric oxideoptical densityphosphate buffered solution proliferating cell nuclear antigen polymerase chain reactionpigment epithelium derived factor protein kinase Cpyridoxamine receptor for AGEs ribonucleasereactive oxygen species revolution(s)per minute Secondsprague dawleystatistical package for the social sciences streptozotocintype1