不同情境下伪装记忆损害时的认知及情绪神经机制分析-cognitive and emotional neural mechanism analysis of disguised memory impairment in different situations.docxVIP

time)wererecordedwhilescanning.What’smore,thestrategiesappliedwhencarryingoutrandomresponseandforgingresponsewererecordedafterscanning.Results1．Thebehavioraldatafromthewordforced-choicepatternindicatedthatthereactiontime(RT)ofrandomresponsewastheshortest,andthereactiontimeofskillresponsewasthelongest.Thereactiontimefromlongtoshortinturnwasskillresponse、truthresponse、wrongresponseandrandomresponse.Comparedwithtruthresponse,theaccuracyofskillresponse、randomresponseandwrongresponsedeclined.Butthedifferenceofaccuracybetweenrandomresponseandskillresponsewasnotsignificant.Theaccuracyoftruthresponsewasthehighest,andthewrongresponsewasthelowest.2.Imagingdataindicatedthattheactivatedbrainregionsweredifferentwhenrespondingskillfullyunderdifferentsituations.Buttheamygdalathoughtasthecontrolcenterofemotionwasnotsignificantlyactivated.Whencomparedwithtruthresponseinawardandpunishmentgroup,thebrainregionssignificantlyactivatedweremorethantruthresponse,andthemainregionsweretheleftmiddlefrontal,therightanteromedialfrontal,thebilateralparietallobeandthefrontoccipital.Incomparisonwithawardgroup,thereweremorebrainregionssignificantlyactivatedinawardandpunishmentgroup,andmostactivatedregionswereintherighthemisphere.ConclusionsDeceptionwasacomplexcognitiveprocessthatinvolvesinmultiplepsychologicalfactors,suchassensoryperception,memory,thought,imaginationandsoon.Thereexistsafrontal-parietal-subcriticalcircuitduringFeigningmemoryimpairment.Theanticipationandtheemotionoffearandanxietywouldbearousedinthesituationofawardandpunishment,andthecognitiveactivityofbrainwasincreasedunderthebackgroundofpsychologicalconflict.keywordsfeign；memoryimpairment;emotion；amygdala；fMRI第1章前言1.1研究意义和目的近年来在司法精神鉴定领域中，涉及精神损伤或精神伤残的刑事民事鉴定案例越来越多，其中相当一部分是对被鉴定人伤后的记忆损害程度进行评定。在鉴定过程中，如何鉴别当事人是否伪装记忆损害，主要依赖受试对记忆测查的合作程度。与传统的司法鉴定专家会诊制度和心理测试以及多道心理生理测试仪（polygraph,又称为测谎仪）不同的是，大脑功能成像技术是一种新型的甄别伪装记忆损害诈病的新技术，相对来说更加敏感客观可靠。本课题首先通过记忆损害模拟伪欺骗装实验，采用区组设计方案，结合两项必选记忆测验和大脑功能磁共振成像（functionalmagneticresonanceimaging，fMRI）扫描，观察受试在认知刺激任务中伪装记忆损害（受试