不同周期stz大鼠vegf的表达及p-akt的激活对心脏缺血再灌注损伤的影响-effects of vegf expression and p - akt activation on myocardial ischemia-reperfusion injury in stz rats in different cycles.docxVIP

的表达。关键词：糖尿病；缺血/再灌注；血管内皮生长素；磷酸化蛋白激酶； 内皮一氧化氮合酶2. AbstractContradictory effects of short- and long-term diabetes on ischemic/reperfusion injury of rats myocardium via VEGF expression and Activation of Cell Survival SignalingThe effect of diabetes on ischemia/reperfusion (I/R) injury is controversial. Some studies show resistance to I/R injury during diabetes but others show increased sensitivity to I/R injury. Our aims were to determine the effects of I/R on myocardial infarction in diabetes and to determine if sensitivity to I/R injury is related to diabetes-induced alterations in VEGF expressio