早发与晚发型重度子痫前期临床对比探析.docVIP

早发与晚发型重度子痫前期临床对比探析 　　[摘要] 目的 探析早发型与晚发型重度子痫前期在临床治疗中的各项情况，如母体并发症、妊娠终止时机、围产儿结局等。方法 对该院2009年3月―2012年5月收治的238例重度子痫前期患者的临床资料进行回顾性对比分析。结果 早发型重度子痫前期患者的舒张压和收缩压显著高于晚发型重度子痫前期患者；早发型重度子痫前期患者的HELLP综合征、胎盘早剥、低蛋白血症、产后出血、眼底病变、肝损害的发生率均显著高于晚发型重度子痫前期患者；早发型重度子痫前期患者的胎死宫内、胎儿窘迫、新生儿轻、新生儿畸形、重度窒息的发生率显著高于晚发型重度子痫前期患者。结论 早发型重度子痫前期和晚发型重度子痫前期在并发症、妊娠终止时机、围产儿结局等方面是存在差异的，在临床治疗中应当对症治疗。 　　[关键词] 重度子痫前期；早发型；晚发型 　　[中图分类号] R714.25 [文献标识码] A [文章编号] 1674-0742（2013）06（c）-0111-02 　　A Comparative Study on Early Onset and Late Onset Severe Preeclampsia 　　LUO Runhuan SUO Dongmei ZENG meng 　　Maternity and Infant Care Assdciation of Foshan city in Guangdong Province，Foshan 528000，China 　　[Abstract] Objective To analyze the characteristics of early and late onset severe preeclampsia involving maternal major complication， termination of pregnancy time， perinatal outcomes， etc. Methods 238 cases of severe preeclampsia patients’ clinical data from March 2009 to May 2012 were retrospectively contrast analysis. Results There were bigger contractive pressure and diastolic pressure in early onset group than in late onset group who had standard antenatal care.There were significant differences in the incidence rate of placental HELLP syndrome， flooding Hypoproteinemia， hepatic dysfunction， eyeground disorder. Early onset severe preeclampsia is easy to have many kinds of complications， affect maternity and perinatals seriously. Conclusion Early hairstyle severe preeclampsia and late onset severe preeclampsia were different in pregnancy complications， terminating time， perinatal outcomes .Clinical treatment should be symptomatic treatment. 　　[Key words] Severe preeclampsia； Early onset； Late onset 　　重度子痫前期是一种妊娠期多系统疾病，对母婴的生命安全与健康有着极大的危害，是导致孕产妇死亡和围产儿死亡的原因之一。重度子痫前期继发于内皮活化与血管痉挛造成器官灌注减少，引发的一系列生理病理变化会导致血液动力性偶联反应，使得血液灌注量不足、血液粘滞，损伤靶器官，产生心、肺、肾、脑等缺血缺氧功能障碍，危及、害孕产妇和围产儿的健康。不同孕周发生的重度子痫前期，其病情、转归等方面均存在着一定的差异。一般情况下，子痫前期发病的孕周越早，脏器损伤程度、孕妇并发症、围产儿结局等方面的情况就越差。晚发型重度子痫前期通常发病于妊娠34周以后，胎儿已经接近成熟，通过规范治疗能够获得理想的效果。为探析早发型与晚发型重度子痫前期在临床治疗中的各项情况，该研究回顾