子宫动脉化疗栓塞治疗子宫瘢妊娠效果研究.docVIP

子宫动脉化疗栓塞治疗子宫瘢痕妊娠效果研究 　　[摘要] 目的 研究和分析采用子宫动脉化疗栓塞治疗剖宫术后子宫瘢痕妊娠的临床效果。方法 随机选择130例该院剖宫产术后子宫瘢痕妊娠患者作为研究对象随机把其分为观察组和对照组，对照组患者只借助B超引导进行清宫术治疗，而观察组则采用在双侧子宫动脉，介入化疗栓塞术结合清宫共同治疗，经过3个月随访，将两组患者的治疗效果进行对比 。结果 经过对患者3个月的随访观察，观察组中患者子宫内包块消失时间以及血清p-HGG值恢复正常的时间分别为（15.2±5.1） d、（26.2±8.5） d，都明显短于对照组，该两组患者的子宫内包块消失时间以及血清p-HGG值恢复正常的时间对比，差异有统计学意义，（P中国论文网 /6/viewhtm　　[关键词] 子宫动脉栓塞术；甲氨蝶呤；剖宫产；子宫瘢痕妊娠 　　[中图分类号] R714.2 [文献标识码] A [文章编号] 1674-0742（2015）08（c）-0108-02 　　Effect of Uterine Arterial Chemoembolization in Treatment of Cesarean Scar Pregnancy 　　SONG Yan-yin 　　Zhuozhou Hospital， Zhuozhou， Hebei Province， 072750 China 　　[Abstract] Objective To study the clinical effect of uterine arterial chemoembolization in the treatment of uterine scar pregnancy after cesarean section. Methods 130 patients with uterine scar after cesarean section in our hospital were selected as the research object and randomized into observation group in which bilateral uterine arterial chemoembolization combined with uterine curettage was performed and control group in which B ultrasound-guided uterine curettage was done. The clinical effects were compared between the two groups after 3 months follow-up. Results 3 months follow-up showed that masses disappear time and serum p-HGG recovery time were （15.2±5.1）d and（26.2±8.5）d in the observation group， significantly less than those in the control group with statistical differences， P?0.05； after treatment， the overall effective rate was higher in the observation group than in the control group with statistically significant differences （100% vs 72.6%， P?0.05）. Conclusion Bilateral uterine arterial chemoembolization is worthy of promotion in the treatment of uterine scar pregnancy after cesarean section. 　　[Key words] Uterine arterial embolization； Methotrexate； Cesarean section； Uterine scar pregnancy 　　近些年来，剖宫产术后瘢痕妊娠的患者呈增加趋势，这种妊娠属于罕见类型的异位妊娠现象之一，主要表现为孕囊着床点在原剖宫产瘢痕处。该病不仅发病率高，而且早期临床症状不突出，给早期诊断造成困难，延误治疗的最佳时机，甚至导致子宫破裂引发大出血等并发症，严重者危及生命和生育机能[1]。从2013年2月―2014年12月间，该该院运用甲氨蝶呤子宫动脉