慢性咽炎伴有胃食管反流病临床分析.docVIP

慢性咽炎伴有胃食管反流病临床分析 　　doi：10.3969/j.issn.1007-614x.2014.15.28 　　摘 要 目的：探讨伴有胃食管反流病的慢性咽炎的临床表现和治疗方法。方法：收治伴有胃食管反流病的慢性咽炎患者60例，随机均分为观察组和对照组。观察组采取麦滋林、莫沙必利和兰索拉唑等治疗，对照组采取麦滋林和莫沙必利治疗，并对患者进行问卷评分和胃镜检查，比较两组在治疗前后的情况。结果：观察组在进行治疗后，临床症状显著减轻，差异具有统计学意义（P0.05）。两组治疗前后咽部炎症的有效率分别为83.3%和36.7%。结论：伴有胃食管反流病的慢性咽炎患者通过服用抑制剂和促动力药效果显著。 　　关键词 慢性咽炎 胃食管反流病 临床分析 　　Clinical analysis of chronic pharyngitis associated with gastroesophageal reflux disease 　　Du Feng 　　The Health Center of Jinling Town，Zhaoyuan City，Shandong 265404 　　Abstract Objective：To explore the clinical manifestations and treatment methods of chronic pharyngitis associated with gastroesophageal reflux disease.Methods：60 patients with chronic pharyngitis associated with gastroesophageal reflux disease were selected.They were randomly divided into the observation group and the control group with 30 cases in each.The observation group were treated with Marzulene-S，mosapride and lansoprazole，while the control group were treated with Marzulene-S and mosapride，and we gave the questionnaire score and gastroscopy for patients.We compared the situation of two groups of patients before and after the treatment.Results：After treatment，the clinical symptoms of the observation group were significantly improved，and the difference was statistically significant（P0.05）.The effective rate of the two groups before and after treatment were 83.3% and 36.7% respectively.Conclusion：The effect of application of inhibitors and prokinetic drugs in the treatment of chronic pharyngitis associated with gastroesophageal reflux disease is significant. 　　Key words Chronic pharyngitis；Gastroesophageal reflux disease；The clinical analysis 　　慢性咽炎为耳鼻喉科中的常见疾病，其发病原因与慢性咽炎、刺激性气体、长期烟酒过度和急性咽炎等有关，尤其与胃食管反流病的关系最为密切[1]。2012年3月-2013年3月收治伴有胃食管反流病的慢性咽炎患者60例，对他们的临床症状进行分析研究，现报告如下。 　　资料与方法 　　2012年3月-2013年3月收治伴有胃食管反流病的慢性咽炎患者60例。随机将患者均分为观察组和对照组，其中男35例，女25例，年龄21～75岁，平均52.5岁，病程3个月～1年。 　　研究方法：①问卷评分标准：以患者临床表现的声音嘶哑、下咽困难、咽喉异物、咽喉痛、咳嗽、反酸等症状的频率和程度进行评分。其程度判断的标准：有症状表现但不影响日常活动，在忍受范围内，为轻度（1分）；有症状表现对日常活动有