丹参注射液对脑梗死患者异常血脂调整作用.docVIP

丹参注射液对脑梗死患者异常血脂调整作用 　　[摘要] 目的 观察丹参注射液对脑梗死患者的血脂影响。 方法 选取2006年10月~2009年11月河北省赵县人民医院血脂异常的脑梗死患者88例，按治疗方法不同分为治疗组46例及对照组42例，治疗组在常规治疗的基础上给予丹参注射液20 mL，1次/d；对照组在常规治疗基础上给予阿托伐他汀钙20 mg，1次/d。治疗14 d后检测两组患者三酰甘油（TG）、总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）、高密度脂蛋白胆固醇（HDL-C）水平；采用神经功能缺损评分量表（CSS）对两组患者神经功能恢复情况进行评估及比较；比较两组总治疗效果。 结果 ①治疗后两组患者的TC、TG、LDL-C水平较治疗前均显著下降，而HDL-C水平显著提高，差异均有统计学意义（P 0.05）。②两组患者CSS评分在治疗的第14、28天时，均明显低于治疗前，差异均有统计学意义（P 　　[关键词] 丹参注射液；脑梗死；血脂异常 　　[中图分类号] R743.3[文献标识码] B[文章编号] 1673-7210（2014）06（b）-0142-04 　　 　　Adjustment of Salvia Injection to dyslipidemia on patients with cerebral infarction 　　WANG Yingxia 　　Department of Internal Medicine, the Peoples Hospital of Zhao County, Hebei Province, Zhao County 051530, China 　　[Abstract] Objective To investigate effect of Salvia Injection to dyslipidemia on patients with cerebral infarction. Methods 88 patients with cerebral infarction and dyslipidemia in Peoples Hospital of Zhao County in Hebei Province were selected and divided into 46 cases in treatment group and 42 cases in control group. The treatment group was treated with Salvia Injection 20 mL, 1 time/d on the bases of basic treatment; the control group was treated with Atorvastatin 20 mg, 1 time/d on the bases of basic treatment. The level of TG, TC, LDL-C, HDL-C in the two groups 14 days after the treatment were detected; the nervous function recovery was evaluated and compared by the CSS scale; the total therapeutic effect was compared between the two groups. Results ①TC, TG, LDL-C level in the two groups after the treatment were all lower than those before the treatment, HDL-C levels in the two groups after the treatment were higher than those before the treatment, the differences were statistically significant (P 0.05). ②CSS scores in the two groups 14 and 28 days after the treatment were all lower than those before the treatment, the differences were statistically significant (P 　　脑梗死是危害人类健康的最严重疾病之一，高龄、高血压、高血脂、糖尿病是其主要的危险因素，脑梗死患者中合并血脂异常者比例较高，占70%～80%，血脂水平异常是动脉壁粥样硬化和脑组织梗死的相关危险因