回肠原位新膀胱患者的无症状菌尿症.docVIP

回肠原位新膀胱患者的无症状菌尿症 Bacteriuria in patients with an orthotopic ileal neobladder: urinary tract infection Or asymptomatic bacteriuria? 回肠原位新膀胱患者的菌尿：尿路感染还是无症狀菌尿症？ Francesca Suriano, Michele Gallucci*, Gerardo Paolo Flammia, Stefania Musco, Antonio Alcini, Gregorio Imbalzano? and Giordano Dicuonzo? Departments of Urology and ?Microbiology, Campus Bio-Medico, and *Regina Elena Cancer Institute, Rome, Italy Accepted for publication 14 September 2007 OBJECTIVE To investigate the prevalence of asymptomatic bacteriuria (ABU) and urinary tract infection (UTI), and the local and systemic inflammatory response, in patients with ileal neobladder. 课题： 对回肠新膀胱患者进行无症状菌尿症和尿路感染以及局部和系统炎症反应的普遍性调查。 PATIENTS AND METHODS The study included 40 patients who had a radical cystectomy and ileal neobladder. Two urine samples, one for chemical and physical analysis, and cytofluorimetry, and one for urine culture, were collected every 3 months for 9 months after surgery. 对象与方法: 对40名进行过膀胱全切的回肠新膀胱的患者进行研究。在其手术后，每隔3~9个月进行尿液采样，并分为两组，一组用于进行化学与物理分析和细胞荧光测定，另一组则进行尿培养。 RESULTS Of 119 urine cultures, 69 (57%) were positive for bacteria. Only nine of the 40 patients had no bacteriuria on urine culture. Escherichia Coli strains were cultured from eight of 10 patients with persistently positive urine. The incidence of bacteriuria was different according to gender. There was a high concentration of leukocytes (0–6μL) in 118 of 119 samples. The mean concentration of leukocytes in sterile urine culture was 1181/μL, while in patients with ABU the mean was 491 (P?0.05). （分析）结果： 尿培养的119份尿样中，69份（占57%）呈阳性。40名患者中仅有4人的尿培养液中无细菌。在呈阳性的患 者中，每10人中便有8人的尿液中存在大肠杆菌群。不同性别菌尿症发病率不同。119份尿样中有118份的白血球浓度极高。在无菌条件下进行的尿培养中，白血球平均浓度为1181/μL，而在菌尿症患者中平均浓度则为491 (P?0.05). CONCLUSION A positive urine culture is a very common finding in patients with an orthotopic bladder.The most interesting results was the absence of elevated inflammatory indices and/or symptoms,