实验性肌炎动物模型制作及il 6在其肌肉组织中表达的研究-establishment of experimental myositis animal model and study on expression of il 6 in its muscle tissue.docxVIP

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实验性肌炎动物模型制作及il 6在其肌肉组织中表达的研究-establishment of experimental myositis animal model and study on expression of il 6 in its muscle tissue.docx

实验性肌炎动物模型制作及il 6在其肌肉组织中表达的研究-establishment of experimental myositis animal model and study on expression of il 6 in its muscle tissue

Theestablishmentofananimalmodelofexperimentalautoimmunemyositisandtheexpressionofinterleukin-6inthemuscleAbstractObjectiveInordertofurtherinvestigatetheunderlyingmechanismsininflammatorymyositis,ananimalmodelofexperimentalautoimmunemyositis(EAM)hasbeengeneratedonguineapigs.Inaddition,anveryimportantfactor,IL-6,hasbeenexploredinthemodel.MethodsAnanimalmodelofexperimentalautoimmunemyositiswasproducedinguinea-pigsbyrabbitskeletalmusclemyosinaddedtoFreund’scompleteadjuvant(CFA),whileguinea-pigsreceivedaninjectionofpertussistoxin(beforetwice).Itwasobservedthatanimalsshowedsymptomsofmyositis,theelev

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实验性肌炎动物模型制作及il 6在其肌肉组织中表达的研究-establishment of experimental myositis animal model and study on expression of il 6 in its muscle tissue.docxVIP