微流控系统的磁泳运动仿真和实验分析-magnetophoresis simulation and experimental analysis of microfluidic system.docxVIP

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微流控系统的磁泳运动仿真和实验分析-magnetophoresis simulation and experimental analysis of microfluidic system.docx

微流控系统的磁泳运动仿真和实验分析-magnetophoresis simulation and experimental analysis of microfluidic system

华 华 中 科 技 大 学 硕 士 学 位 论 文 II万方数据 II 万方数据 体磁泳运动的影响,对磁性微粒的磁泳聚集行为做出预测。 搭建微流控平台,进行实验研究。验证了有限元仿真模型下的磁泳运动现象, 可以看出与理论研究基本吻合。 限于实验条件及工作展开,本文对微流控系统下的磁泳运动作了基础理论的相 关研究,开展了磁泳运动的仿真和相关基础实验,尚有许多待解决问题,对于磁流 体的混合、分离的问题有待进一步研究,引进更为精密的微管道制作方案和用于磁 泳运动观测的设备,也将会大大提高对磁流体磁泳运动的研究认知。 关键词:微流控系统;磁泳运动;数值模型;有限元分析;磁泳预测 III万方数据 III 万方数据 Abstract Microfluidic technology involves interdisciplinary engineering, physics, chemistry, material science, fluid mechanics, electromagnetics, micro processing and biological engineering and some other related fields. The technique involves the basic operations such as sampling, reagent, reaction mixture, detection and isolation of and so on, and has high efficiency, save the sample, high integration and low cost requirements, which has very broad application prospects. With the development of nano-magnetic materials, due to its good superparamagnetism, biocompatibility, and stability, and easily to realize of biochemical modification, we can realize controllable magnetic particles under action of magnetic field, microfluidic technology based on nano-magnetic materials has got more attention and research. Particles moving under magnetic field called magnetophoretic. Based on microfluidic technology combined with magnetic field, the carrier magnetic particles has been concerned by many scholars all over the world in recent years and so is research on magnetophoretic. This paper has analyzed the stress of magnetophoretic under gradient magnetic field and flow field based on the theory of fluid mechanics and electromagnetics and has taken the exploration and research of magnetophoretic in micro pipe through theoretical analysis, finite element numerical simulation and experimental verification. The main research contents are as follows: Numerical model on magnetophoretic of micro magnetic particles under gradient magnetic field and flow field is established. Through cylindrical permanent magnet as the magnetic source, analytical expressions of the two-di

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