HR―HPVTCT分别联合电子阴道镜下宫颈活检在宫颈癌前病变及宫颈癌诊断中应用.docVIP

HR―HPVTCT分别联合电子阴道镜下宫颈活检在宫颈癌前病变及宫颈癌诊断中应用 　　[摘要] 目的 探究高危型人乳头瘤病毒（HR-HPV）检测、液基细胞学检查（TCT）分别联合电子阴道镜下宫颈活检对宫颈癌前病变及宫颈癌的诊断价值。 方法 回顾性分析2013年1～12月TCT+电子阴道镜+宫颈活检病历400例，2014年1～12月HR-HPV+电子阴道镜+宫颈活检400例，比较两种检查方法的阳性率。 结果 TCT+电子阴道镜+宫颈活检的检出阳性率为10.75%（43/400），HR-HPV+电子阴道镜+宫颈活检的检出阳性率为11.75%（47/400），两种检查方法阳性检出率的比较，差异无统计学意义（χ2=0.200，P0.05）。 结论 HR-HPV+电子阴道镜+宫颈活检与TCT+电子阴道镜+宫颈活检均具有较高的宫颈癌前病变及宫颈癌的检出率，有利于宫颈癌前病变和宫颈癌的早发现、早治疗，均是比较理想的检查方法。 　　[关键词] 宫颈癌；宫颈癌前病变；HR-HPV检测；TCT；电子阴道镜；宫颈活检 　　[中图分类号] R711.74 [文献标识码] A [文章编号] 1674-4721（2016）01（b）-0065-03 　　Application of HR-HPV，TCT combined with cervical biopsy under electronic colposcope respectively in the diagnosis of precancerous lesion of uterine cervix and cervical cancer 　　YAN Qi HUANG Wen-jin ZENG Chao-yi WEN Hong-lei 　　The Seventh People′s Hospital in Nanhai District of Foshan City in Guangdong Province，Foshan 528247，China 　　[Abstract] Objective To explore the diagnostic value of high-risk human papillomavirus （HR-HPV） test，thinprep cytologic test （TCT） combined with cervical biopsy under electronic colposcope respectively in the diagnosis of precancerous lesion of uterine cervix and cervical cancer. Methods Four hundred medical records of TCT，electronic colposcope and cervical biopsy from January to December 2013 and 400 medical cases by HR-HPV，electronic colposcope and cervical biopsy from January to December 2014 were retrospectively analyzed，and the positive rate of two kinds of inspection method was compared. Results For the TCT，electronic colposcope and cervical biopsy，the positive rate of detection was 10.75% （43/400），while for HR-HPV，electronic colposcope and cervical biopsy，the positive rate of detection was 11.75% （47/400），and there was no statistical difference between two kinds of inspection method （P0.05）. Conclusion HR-HPV，electronic colposcope and cervical biopsy， and TCT，electronic colposcope and cervical biopsy have higher detection rate on precancerous lesions of uterine cervix and cervical cancer，which are beneficial for e