NSTEACS患者冠脉病变特点与心功能不全研究.docVIP

NSTEACS患者冠脉病变特点与心功能不全研究 　　基金项目：沈阳医学院科技基金项目（项目编号? 　　作者单位：110002中国医科大学（王晓萍）；中国医科大学附属盛京医院（孙志军）；沈阳医学院沈洲医院（吴蔚，邵冰，秦莹，宋平南，孙琳）? 　　通讯作者：孙志军 　　【摘要】 目的 研究NSTE-ACS患者冠状动脉病变特点和心功能不全的关系。方法 选择445例NSTE-ACS患者随机分为NSTEMI（140例）组和UA组(305例)，回顾性分析入选者的住院病历资料，比较两组基线资料、冠状动脉造影结果和支架情况，总结NSTEMI组患者冠脉病变特点与心功能不全的关系。结果 NSTEMI组的三支病变、左主干病变的例数高于UA组（?P?0.05）；NSTEMI组的弥漫性病变、次全闭塞和完全闭塞、侧支循环的例数显著高于UA组（?P?0.01）；Logistic回归分析显示影响NSTE-ACS患者心功能不全事件的因素是空腹血糖升高、入院时心率、三支病变、LAD近段次全闭塞和完全闭塞病变、支架总长度。结论 NSTEMI组患者多支血管病变常见,病变范围广,病变程度严重，心功能不全发生率较高。? 　　【关键词】 冠状动脉疾病； 心功能不全； 冠状动脉造影?? 　　Characteristics of coronary lesions in NSTE-ACS patients with heart dysfunction ?WANG Xiao-ping?*,SUN Zhi-jun,WU Wei,et al.?*China Medical University,Shenyang 110002,China?? 　　【Abstract】 Objective To research the patients of NSTE-ACS,whose relationship coronary artery disease with heart failure characterized.Methods 425 NSTE-ACS patients were randomly divided into NSTEMI (155 cases) group and the UA group (270 cases),retrospective analysis patient?s medical records,Baseline data,the results of coronary angiography and stent case were compared.Summary NSTEMI patients? relationship between the coronary artery disease and heart failure characterized.Results NSTEMI group of three-vessel disease,left main disease greater than the number of patients in UA group（?P?0.05）;NSTEMI group of diffuse lesions,and subtotal occlusion and complete occlusion,collateral circulation was significantly higher than the number of patients in UA group（?P?0.01）;Logistic regression analysis showed that affected patients with NSTE-ACS factor in heart failure events was elevated fasting glucose,admission heart rate,three-vessel disease,LAD proximal subtotal occlusion and total occlusion,stent length.Conclusion NSTEMI group of patients with multiple vessel disease in common;a wide range of diseases,severe lesions,a higher incidence of cardiac dysfunction in NSTEMI group.? 　　【Key words】 Coronary artery disease； Heart failure； Coronary angiography 　　??