cTnI及hsCRP在急性心肌梗死诊断中临床价值.docVIP

cTnI及hsCRP在急性心肌梗死诊断中临床价值 　　 　　[摘要] 目的 分析心肌肌钙蛋白I（cTnI）及高敏C反应蛋白（hs-CRP）在急性心肌梗死诊断中的临床价值。 方法 随机选取本院2013年1～12月收治的48例急性心肌梗死患者作为治疗组，同时选取同期到本院就诊的48例健康体检人员作为对照组，检测两组患者的cTnI及hs-CRP水平。 结果 治疗组cTnI及hs-CRP水平显著高于对照组，差异有统计学意义（P0.05）。治疗组患者cTnI在4～8 h升高，高峰在8～12 h，72 h后降低；hs-CRP不断升高，高峰在12～24 h，72 h后降低到正常水平。 结论 联合检测cTnI及hs-CRP，对诊断急性心肌梗死具有较高的临床价值，值得临床推广应用。 　　[关键词] 心肌肌钙蛋白I；高敏C反应蛋白；急性心肌梗死 　　[中图分类号] R542.2+2[文献标识码] A[文章编号] 1674-4721（2014）05（a）-0081-02 　　 　　Clinical value of cTnI and hs-CRP in the diagnosis of acute myocardial infarction 　　LI Hai-lin1 LIU Guo-zhong2 　　1.Jian Center Blood Bank in Jiangxi Province,Jian 343000,China;2.Jian Central People′s Hospital in Jiangxi Province,Jian 343000,China 　　[Abstract] Objective To analyze the clinical value of cardiac troponin I (cTnI) and high sensitive C-reactive protein (hs-CRP) in the diagnosis of acute myocardial infarction.Methods 48 cases of patients with acute myocardial infarction in our hospital from January to December 2013 were selected as treatment group,and 48 cases of healthy people in our hospital were as control group,cTnI and hs-CRP of two patients were detected.Results cTnI and hs-CRP in the treatment group was significantly higher than that in the control group respectively,the difference was significant (P0.05).cTnI of the treatment group increased in 4-8 h,the peak was at 8-12 h,72 h decreased; hs-CRP increased continuously,the peak was at 12-24 h,72 h decreased to normal level.Conclusion The combined detection of cTnI and hs-CRP has high clinical value in the diagnosis of acute myocardial infarction,is worth the clinical promotion. 　　[Key words] Cardiac troponin I;High sensitive C-reactive protein;Acute myocardial infarction 　　急性心肌梗死是由于冠状动脉急性闭塞血流中断，导致心肌具备缺血性坏死，临床表现为休克、心律失常、胸骨后疼痛等症状，因此必须要做好急性心肌梗死的诊断工作，采取积极有效的措施进行救治[1-2]。目前在诊断急性心肌梗死时，主要是通过患者病史、临床症状、心电图特征性改变及心肌损伤等生化指标。根据实验室检查可全面反映患者的病情变化，检测患者血清中的心肌肌钙蛋白I（cTnI）及高敏C反应蛋白（hs-CRP）水平，对诊断患者急性心肌梗死具有积极的指导意义。 　　1 资料与方法 　　1.1 一般资料 　　随机选取本院2013年1～12月收治的48例急性心肌梗死患者作为治疗组，其中男26例