OSA―18量表评估儿童阻塞性睡眠呼吸暂停低通气综合征疗效可行性分析.docVIP

OSA―18量表评估儿童阻塞性睡眠呼吸暂停低通气综合征疗效可行性分析 　　【摘要】 目的：探讨儿童OSAHS特异性生活质量调查（Disease specific quality of for children with obstructive sleep apnea 18 items survey，OSA-18）量表评估儿童阻塞性睡眠呼吸暂停低通气综合征（Structive sleep apnea hypopnea syndrome，OSAHS）疗效的可行性分析。方法：选取2015年5月-2016年12月于本院诊治的轻度OSAHS患儿60例为研究对象，按照随机数字表法将其分为药物治疗组和未用药物组，各30例，药物治疗组给予局部内固醇喷鼻剂治疗，未用药物组不给予药物治疗，随访观察3个月。治疗前后均行多道睡眠描记术（Polysomnography，PSG）及采用OSA-18量表评估患儿的治疗效果，分析轻度OSAHS儿童的呼吸暂停低通气指数（Pnea hypopnea index，AHI）和最低血氧饱和度（Lowest oxygen saturation，LSaO2）与OSA-18评分的相关性。结果：治疗后，药物治疗组AHI低于治疗前及同期未用药物组（P0.05）；治疗后，药物治疗组睡眠障碍、身体症状、对监护人影响及总分均低于治疗前及同期未用药物组，比较差异均有统计学意义（P0.05）；OSA-18各项指标评分及总分与AHI均呈正相关（P0.05），除对监护人影响外，OSA-18其余各项指标评分及总分与LSaO2均呈负相关（P0.05）。结论：OSA-18评分?cPSG存在相关关系，可作为临床评价儿童OSAHS的疗效指标。 　　【关键词】 OSA-18量表； 阻塞性睡眠呼吸暂停低通气综合征； 多道睡眠描记术 　　Feasibility Analysis of OSA-18 Questionnaire in Assessment Efficacy of Children with Structive Sleep Apnea Hypopnea Syndrome/PAN Yong，FAN Shaochong，ZHONG Xiaosheng，et al.//Medical Innovation of China，2017，14（32）：010-013 　　【Abstract】 Objective：To explore the feasibility analysis of disease specific quality of for children with obstructive sleep apnea 18 items survey（OSA-18） questionnaire in assessment efficacy of children with structive sleep apnea hypopnea syndrome（OSAHS）.Method：60 children with mild OSAHS diagnosed and treated in our hospital from May 2015 to December 2016 were selected，according to the random number table method，they were divided into drug treatment group and non medication group，30 cases in each group，the drug treatment group was given local steroid nasal spray，and non medication group was not given medication，followed up for 3 months.Before and after treatment，polysomnography（PSG） and OSA-18 questionnaire were used to evaluate the treatment effect，to analyze the correlation between pnea hypopnea index（AHI），lowest oxygen saturation（LSaO2） and OSA-18 questionnaire in mild OSAHS children.Result：After treatment，AHI in drug treatment group was lower than that of before treatment and the same pe