NT―proBNP对妊娠高血压疾病孕妇心脏功能评价.docVIP

NT―proBNP对妊娠高血压疾病孕妇心脏功能评价 　　[摘要] 目的 探讨NT-proBNP评价妊娠高血压疾病孕妇心功能的临床效果。方法 方便选取2015年5月―2017年5月该院收治的136例妊娠高血压疾病孕妇为研究对象，依疾病类别不同分为实验1组（妊娠期高血压，42例）、实验2组（子痫前期，55例）、实验3组（子痫，39例），另择取同期该院45名健康孕妇为对照组。全部患者均于终止妊娠前检测血清NT-proBNP水平和心肌酶指标，对比观察各组心功能分级。结果 实验3组NT-proBNP（796.5±63.1）pg/mL， 肌酸激酶同工酶（78.3±19.2）ng/mL，肌红蛋白（65.5±2.4）ng/mL，心功能III～IV级97.5%，各项指标均高于对照组和实验1、2组。结论 血清NT-proBNP会随着妊高症病情和心脏损害的加重而升高，可作为评价妊娠高血压疾病孕妇心功能水平的敏感指标在临床推广使用。 　　[关键词] 妊娠高血压疾病；NT-proBNP；心功能 　　[中图分类号] R714 [文献标识码] A [文章编号] 1674-0742（2017）09（b）-0059-03 　　[Abstract] Objective This paper tries to evaluate the clinical effect of NT-proBNP on cardiac function in pregnant women with pregnancy induced hypertension. Methods Convenient selection 136 cases of hypertensive disorders complicating pregnancy women from May 2015 to May 2017 in this hospital were selected as the research objects， according to the different categories of diseases， these patients were divided into the experimental group one（gestational hypertension， 42 cases）， group two（preeclampsia， 55 cases）， and the experimental group three（eclampsia， 39 cases）， another 45 cases of healthy pregnant women of the same period were selected as the control group. All patients were tested for serum NT-proBNP levels and myocardial enzymes before termination of pregnancy， and the classification of cardiac function was observed in each group. Results In the experimental group three， the NT-proBNP was （796.5±63.1）pg/mL， creatine kinase isoenzyme was（78.3±19.2）ng/mL， myoglobin was（65.5±2.4）ng/mL， heart function of III～IV level was 97.5%， all indexes were higher than the control group and the experiment group one and two. Conclusion Serum NT-proBNP may increase with the aggravation of hypertensive disorders complicating pregnancy and heart damage. It can be used as a sensitive index to evaluate the cardiac function of pregnant women with hypertensive disorders complicating pregnancy. 　　[Key words] Hypertensive disorders complicating pregnancy； NT-proBNP； Cardiac function