B超引导经皮肝穿射频治疗肝癌24例临床研究.docVIP

B超引导经皮肝穿射频治疗肝癌24例临床研究 　　[摘要] 目的 探讨肝癌患者实施经皮肝穿射频治疗的效果。 方法 回顾性分析2006年11月～2011年1月本院24例肝脏恶性肿瘤患者行B超引导经皮肝穿射频治疗的临床资料。 结果 24例患者中，16例患者15min吲哚靛青绿储留率（ICGR 15）20%；甲胎蛋白提示阳性患者经治疗后转为阴性的有75.0%，呈明显下降的有25.0%；CT复查显示肿瘤缩小，完全凝固性的坏死率是87.5%。 结论 对于肝癌患者，尤其是重度肝硬化、肝功能较差、不耐手术、术后复发者，实施RF治疗不仅创伤小，而且方便、安全，疗效确切，应予临床合理推广。 　　[关键词] 肝脏肿瘤；射频治疗；B超引导；临床研究 　　[中图分类号] R735.7 [文献标识码] B [文章编号] 2095-0616（2014）04-177-02 　　Clinical study of ultrasound-guided percutaneous radipfrequency ablation in 24 cases with liver cancer 　　WANG Naijie 　　Department of Surgery，Hospital of Traditional Chinese Medicine of Daliutun in Xinmin City，Xinmin 110300，China 　　[Abstract] Objective To explore the clinical effect of ultrasound-guided percutaneous radiofrequency ablation in treating patients with liver cancer. Methods Clinical data of 24 patients with liver cancer who were treated using ultrasound-guided percutaneous radiofrequency ablation in our hospital from November 2006 to January 2011 was retrospectively analyzed. Results In 24 patients， the indocyanine green retention rate in 15 minutes （ICGR 15） was less than 10% in 16 cases，10%-20% in 5 cases and more than 20% in 3 cases. 75.0% of AFP-positive patients turned to be negative after the treatment and 25.0% of patients had significant decrease.CT scan results showed tumor shrinkage and the necrosis rate of complete coagulation was 87.5%. Conclusion Radiofrequency ablation should be promoted clinically with minimum invasion，good safety and efficacy in the treatment of liver cancer， especially for those patients with severe liver cirrhosis， poor liver function，non-resistance to surgery and postoperative occurrence. 　　[Key words] Liver cancer；Radiofrequency ablation；Ultrasound-guidance；Clinical study 　　肝脏恶性肿瘤是消化系统发病率较高肿瘤[1]，包括原发性肝癌和转移性肝癌，传统的治疗方法有手术切除、全身化疗、放射治疗[2]、中医中药治疗、免疫治疗等[3]。RF（经皮肝穿射频）是近年发展起来的肝癌患者姑息治疗的一种微创手术[4]，是肝癌治疗的第三大手段。2008年1月～2012年6月，对我院收治的24例肝脏恶性肿瘤患者，在超声引导下给予RF治疗，取得了很好的临床效果，报道如下。 　　1 资料与方法 　　1.1 一般资料 　　收集我院收治的24例肝脏恶性肿瘤患者，其中男18例，女6例；患者年龄最大为75岁，最小为31岁，平均年