上饶区域儿童性早熟流行特征及相关危险因素研究.docVIP

上饶区域儿童性早熟的流行特征及相关危险因素研究 　　[摘要]目的 研究分析地方儿童性早熟的流行特征及相关危险因素。方法 选取2015年3月～2017年3月我院收治的125例性早熟患儿作为研究对象，设为研究组，选取同期于我院进行健康体检的正常儿童125例作为对照组。收集所有研究对象的临床资料并进行回顾性分析，所有研究对象均进行骨龄、雌二醇、卵泡刺激性素、睾酮、黄体生成素检测，分析两组研究对象的相关信息，了解儿童性早熟的流行特征，并分析其相关危险因素。结果 儿童性早熟与家庭附近环境污染、母亲职业、母亲初潮年龄、母亲妊娠期间是否保胎、父母关系是否协调、是否有性早熟家族史、居住区域、出生时体重、爱看情感类节目和小说、食用洋快餐、食用营养滋补品、食用含色素和防腐剂食品、食用高蛋白食品等有关（P0.05）。居住区域、爱看情感类节目和小说、经常食用洋快餐、经常食用营养滋补品、经常食用含色素和防腐剂食品、经常食用高蛋白食品是儿童性早熟的独立危险因素（P0.05）。结论 儿童性早熟受多方面因素的影响，合理饮食、正确抚育、创造良好环境等有助于减少儿童性早熟的发生。 　　[关键词]儿童性早熟；流行特征；相关危险因素 　　[中图分类号] R339.31 [文献标识码] A [文章编号] 1674-4721（2018）2（a）-0135-03 　　[Abstract]Objective To study and analyze the epidemiological characteristics and related risk factors of precocious puberty in local children.Methods A total of 125 children with precocious puberty treated in our hospital from March 2015 to March 2017 were selected as the study group and 125 healthy children underwent physical examination in our hospital were selected as the control group.The clinical data of all the subjects were collected and analyzed retrospectively.All subjects were tested for bone age，estradiol，follicle stimulating hormone，test osterone and luteinizing hormone.The related information of two groups of subjects was analyzed to understand the epidemiological characteristics of precocious puberty in children，and the related risk factors was analyzed.Results Children′s precocious puberty was related to the family environment pollution nearby，mother′s occupation，mother′s age of menarche，whether the mother protect fetus during pregnancy，whether parents relationship coordination，whether a family history of premature，living area，birth weight，like emotional shows and novels，eat western fast food，eat nutrition tonic，eat food contains pigment and preservative，eat high protein food and so on （P0.05）.Living area，liked emotional programs and novels，often eat western fast food，often eat nutrition tonic，often eat food contains pigment and preservative，often eat high protein food were the independe