丁苯酞治疗急性脑缺血引起肢体活动障碍临床观察.docVIP

丁苯酞治疗急性脑缺血引起肢体活动障碍的临床观察 　　[摘要] 目的：观察丁苯酞胶囊治疗急性期脑梗死患者引起肢体障碍的临床疗效。方法：将126例脑梗死患者在常规神经内科处理的基础上随机分成两组，对照组用0.9%氯化钠溶液250 ml加血塞通冻干粉400 mg静点。治疗组用0.9%氯化钠溶液加复方丹参注射液16 ml每日静点1次，另加口服丁苯酞软胶囊1次2粒，1 d 4次。两组均14 d为1个疗程。结果：疗程结束后，患者上、下肢肌力均有明显改善。经过1个疗程的治疗对照组Barthel指数由42.25上升到68.50，而治疗组Barthel指数由41.20上升到83.50。治疗前后比较，P0.01，差异具有统计学意义。结论：丁苯酞软胶囊对于脑缺血发作的患者具有明显的改善肢体功能作用，有较好的临床疗效。 　　[关键词] 脑梗死；丁苯酞；临床观察；肢体活动障碍 　　[中图分类号] R743 [文献标识码] B [文章编号] 1674-4721（2011）12（b）-070-02 　　 　　Clinical observation of the limb moving obstacle caused by acute cerebral ischemia in treatment with butylenyl phthaline 　　WU Wanhua, HE Liansheng 　　Changyi Hospital in Jilin City, Jilin Province, Jilin 132002, China 　　[Abstract] Objective: To observate the clinical curative effect of butylenyl phthaline capsule in the treatment of patients with limb moving obstacle caused by acute cerebral infarction. Methods: One hundred and twenty six cases of cerebral infarction patients in treatment on the basis of general neurology were divided into two groups, control group were treated with 0.9% normal saline 250 ml and Xuesaitong powder 400 mg. Treatment group were treated with 0.9% saline solution and compound danshen injections 16 ml, 1 time a day, oral butylenyl phthaline soft capsule in treatment group two capsules each time, four times a day, 14 days for a course. Results: After the end of the course, upper and lower limb muscle strength in patients was improved markedly. Barthel index of control group rose to 68.50 from 42.25, Barthel index of treatment group rose to 83.50 from 41.20, the difference was statistically significant (P0.01). Conclusion: Butylenyl phthaline soft capsule for patients with cerebral ischemic attack has a significant role in improving limb function, there is better clinical curative effect. 　　[Key words] Cerebral infarction; Butylenyl phthaline; Clinical observation; Limb moving obstacle 　　 　　近年来随着脑缺血疾病的发病率逐年增加，相应的治疗手段匮乏，具有好的临床疗效的药物更是缺乏。临床上多为中药提纯单复方制剂，具有活血化瘀，改善微循环的作用。但作用有限。本院近2年来利用石药集团恩必普药业生产的丁