丁苯酞注射液联合疏血通治疗进展性脑梗死临床疗效探讨.docVIP

丁苯酞注射液联合疏血通治疗进展性脑梗死的临床疗效探讨 　　[摘要] 目的 探讨用丁苯酞注射液联合疏血通治疗进展性脑梗死的临床疗效。方法 将整群选取2013年8月―2015年3月来院就诊的122例患者随机分为两组，将治疗组61例应用丁苯酞注射液联合疏血通治疗的疗效与对照组61例仅给予疏血通治疗的疗效进行比较观察。 结果 治疗组显效36例（59.02%），总有效率88.53%，显著好于对照组72.13%的总有效率（P0.05），同时治疗组患者神经功能缺损程度评分显著降低（P0.05）。 结论 用丁苯酞注射液联合疏血通治疗进展性脑梗死意义重大，其不仅能有效缓解患者的临床症状，还能低患者神经功能缺损程度评分，值得推广应用。 　　[关键字] 丁苯酞注射液；疏血通；进展性脑梗死；疗效观察 　　[中图分类号] R4 [文献标识码] A [文章编号] 1674-0742（2015）09（c）-0106-02 　　[Abstract] Objective To observe the clinical effect of butylphthalide injection and shuxuetong on treating progressive cerebral infarction. Methods 122 patients who came our hospital from August 2015 to March 2013 were randomly divided into two groups.61 patients in the treatment group gave the butylphthalide injection associated with shuxuetong and 61 patients only gave the shuxuetong in the control group. Comparing the clinical effect between these two groups. Results The treatment group has 36 cases （59.02%） who have signal effect. And its total effectiveness is 88.53%， which is significantly better than that in the control group. The total effectiveness of control group is only 72.13% （P 0.05）. And the score of neurological impairment in treatment group patients has obviously declined （P0.05）. Conclusion Butylphthalide injection combined with shuxuetong treatment of progressive cerebral infarction is significant. It not only can effectively alleviate the symptoms of the patients， but also can reduce neurologic impairment score. So it should be widely applied. 　　[Key words] Butylphthalide injection； Shuxuetong； Progressive cerebral infarction； Effect observation 　　进展性脑梗死是指发病后6～48 h内神经功能缺损症状逐渐加重，直至出现神经功能严重损害的一类脑梗死，其是急性脑梗死中严重的临床亚型之一，发病率占总发病率的40%。疏血通注射液是由中药水蛭、地龙组成的黄色澄明溶液，具有活血化瘀、活络通经的功效，是治疗急性期脑梗死的常用药物，而丁苯酞注射液是第一个应用于缺血性脑梗死多个病理环节的新型药物，将两者合用治疗进展性脑梗死具有重要意义。该组将整群选取2013年8月―2015年3月来院就诊的进展性脑梗死患者122例随机分为治疗组及对照组，通过观察丁苯酞注射液联合疏血通治疗进展性脑梗死的临床疗效收到了较好效果，现报道如下。 　　1 资料与方法 　　1.1 一般资料 　　研究将整群选取该院就诊的进展性脑梗死患者122例随机分为治疗组及对照组，病例纳入标准为：①所有患者均经核磁共振等检查确诊为脑梗死并且在发病48 h内出现加重情况，符合中华医学会第四次全国脑血