丁苯酞联合奥扎格雷钠治疗急性脑梗死效果评价.docVIP

丁苯酞联合奥扎格雷钠治疗急性脑梗死的效果评价 　　[摘要] 目的 观察丁苯酞、奥扎格雷钠联合治疗急性脑梗死（ACI）的临床效果。 方法 将本院2012年9月～2013年8月收治的68例急性脑梗死患者纳入研究，在常规治疗的基础上，对照组加用丁苯酞治疗，研究组加用丁苯酞和奥扎格雷钠治疗，比较两组患者的疗效、CSS及生活能力评分。 结果 对照组总有效率为70.59%，研究组总有效率为91.18%，差异有统计学意义（P＜0.05）；两组患者神经功能缺损、生活能力评分差异有统计学意义（P＜0.05）。 结论 丁苯酞联合奥扎格雷治疗ACI的疗效确切。 　　[关键词] 急性脑梗死；奥扎格雷钠；丁苯酞 　　[中图分类号] R743[文献标识码] A[文章编号] 1674-4721（2014）03（c）-0066-03 　　 　　Effect evaluation of butylphthalide combined with sodium ozagrel in treatment of acute cerebral infarction 　　CAI Jing-jie1 HAN Yu-hua2 PANG Tao1 CAO Fei3▲ 　　1.The First Neurology Department,the First People′s Hospital of Zhengzhou City,Zhengzhou 450000,China;2.The Second Neurology Department,the Central Hospital of Xinxiang City in Henan Province,Xinxiang 453000,China;3.Neurology Department,Union Hospital Tongji Medical College Huazhong University of Science and Technology,Wuhan 430074,China 　　[Abstract] Objective To observe the clinical effect of butylphthalide combined with sodium ozagrel in treatment of acute cerebral infarction. Methods 68 cases with acute cerebral infarction were selected as the research object in our hospital from September 2012 to August 2013,on the basis of routine therapy,the control group add in butylphthalide treated,the study group add in butylphthalide combined with sodium ozagrel treated,the curative effect,CSS and life ability score of two groups were compared. Results The total effective rate in control group was 70.59%,the total effective rate in control group was 91.18%,the difference was statistically significant (P0.05).The nerve function defect,life ability score in two groups of patients,the difference was statistically significant (P0.05). Conclusion The butylphthalide combined with sodium ozagrel in treatment of acute cerebral infarction has curative effect. 　　[Key words] Acute cerebral infarction;Sodium ozagrel;Butylphthalide 　　脑梗死是脑卒中的一类，主要是指脑组织血液循环障碍，病变血管供血区域的脑组织及神经细胞由于缺血缺氧而发生坏死[1-2]。随着当前社会人口老龄化趋势的加剧，脑血管疾病愈发成为最主要的致残、致死性疾病之一。患者多为突然发病，病情进展迅速，症状一般较危重，治疗难度大，致死致残