保乳保腋窝手术治疗T1期乳腺癌86例分析.docVIP

保乳保腋窝手术治疗T1期乳腺癌86例分析 　　[摘要]目的 观察T1期乳腺癌行保乳保腋窝手术的治疗效果。方法 回顾性分析2009年8月～2014年10月我院收治的86例行保乳保腋窝手术的T1期乳腺癌患者的临床资料，观察患者的手术并发症、术后乳房美学效果及肿瘤大小与预后的关系。结果 86例患者的手术切口均Ⅰ期愈合，均无患肢淋巴水肿发生，术后乳房美学效果满意度为96.5%（83/86）。肿瘤直径≤1 cm组共40例（1组），前哨淋巴结阳性率为0（0/40）；1 cm肿瘤直径≤2 cm组共46例（2组），前哨淋巴结阳性率为15.2%（7/46），两组患者的前哨淋巴结阳性率比较差异有统计学意义（P0.05）。1组生存率略高于2组，但差异无统计学意义（P0.05）。全部病例均随访，随访时间24～87个月，中位随访时间为50个月，均无复发及转移。结论 保乳保腋窝手术治疗T1期乳腺癌，效果好，并发症少，值得临床应用。 　　[关键词]T1期乳腺癌；保乳保腋窝手术；前哨淋巴结；美学效果 　　[中图分类号] R737.9 [文献标识码] A [文章编号] 1674-4721（2017）03（b）-0069-04 　　[Abstract]Objective The observe the therapeutic effect of breast and axillary reservation operation for stage T1 breast cancer.Methods The clinical data of 86 patients with stage T1 breast cancer who underwent breast and axillary reservation operation treated in our hospital form August 2009 to October 2014 were retrospectively analysed.The postoperative complications，the effect of breast aesthetics and the relationship between tumor size and prognosis were analyzed.Results Surgical incision in 86 patients with stage Ⅰ healing，no limb lymphedema，postoperative satisfaction effects on aesthetics of breast was 96.5% （83/86）.The tumor diameter less than 1 cm were 40 cases （group 1），the positive rate of sentinel lymph nodes was 0 （0/40）；tumor diameter more than 1 cm and less than 2 cm were 46 cases （group 2），the positive rate of sentinel lymph nodes was 15.2% （7/46）.There was significant difference in the positive rate of sentinel lymph node between two groups （P0.05）.Further survival analysis showed that the survival rate of the group 1 was slightly higher than that of group 2，but the difference was not statistically significant （P0.05）.All cases were followed up for 24-87 months，the median follow-up time of 50 months，and no recurrence and metastasis were found.Conclusion Breast and axillary reservation operation in the treatment of stage T1 breast cancer has good effect and few complications，which is worthy of clinical application. 　　[Key words]Stage T1 breast cancer