丙泊酚复合地佐辛靶控输注在妇科腔镜手术全身麻醉中应用效果观察.docVIP

丙泊酚复合地佐辛靶控输注在妇科腔镜手术全身麻醉中的应用效果观察 　　[摘要] 目的 探究丙泊酚复合地佐辛靶控输注在妇科腔镜手术全身麻醉中的应用效果。 方法 选取我院2014年11月～2015年11月收治的行妇科腔镜手术全身麻醉患者共91例，随机分为对照组与观察组，对照组接受丙泊酚复合瑞芬太尼靶控输注，观察组接受丙泊酚复合地佐辛靶控输注。比较两组患者不同时间点血流动力学指标、麻醉效果及不良反应发生率。 结果 两组患者T0时MAP、HR、SaO2%及RR差异无统计学意义（P0.05）。观察组T1、T2、T3及T4时ΔMAP、ΔHR、ΔSaO2%及ΔRR均明显低于对照组（P0.05）。观察组丙泊酚使用量为（413.1±18.4）mg、VAS评分为（3.15±0.35），不良反应发生率为4.3%，均明显低于对照组（P0.05）。 结论 丙泊酚复合地佐辛靶控输注可有效稳定术中循环，减少丙泊酚使用量及降低不良反应发生率，镇痛效果好，值得临床推广应用。 　　[关键词] 丙泊酚；地佐辛；靶控输注；全身麻醉；妇科腔镜手术 　　[中图分类号] R971+.2 [文献标识码] A [文章编号] 1674-4721（2016）04（b）-0116-03 　　[Abstract] Objective To explore the application effects of propofol combined with target-controlled infusion dezocine in gynecological laparoscopic surgery with general anesthesia. Methods 91 cases gynecological laparoscopic surgery with general anesthesia patients from November 2014 to November 2015 in our hospital were selected and were randomly divided into control group and observation group.Patients in control group were given propofol combined with target-controlled infusion remifentanil.Patients in observation group were given propofol combined with target-controlled infusion dezocine.The hemodynamic index，anesthesia effects and the incidence rate of adverse effects at different times between two groups were compared. Results The MAP，HR，SaO2% and RR at T0 between two groups had no obvious difference （P0.05）.The ΔMAP，ΔHR，ΔSaO2% and ΔRR in observation group at T1，T2，T3 and T4 were obvious lower than those in control group （P0.05）.The propofol usage amount，VAS score and incidence rate of adverse effects in observation group was respectively （413.1±18.4）mg，（3.15±0.35） and 4.3%，which was obvious lower than that in control group （P0.05）. Conclusion Propofol combined with target-controlled infusion dezocine can maintain the circulation stable effectively，decrease the usage amount of propofol， has less incidence rate of adverse effects and good analgesic effect.It is worth to popularize in clinic. 　　[Key words] Propofol；Dezocine；Target-controlled