妇产科手术的预防性抗生素应用分析.docVIP

妇产科手术的预防性抗生素应用分析 　　doi：10.3969/j.issn.1007-614x.2014.11.6 　　摘 要 目的：探讨妇产科手术预防性应用抗生素的临床疗效。方法：收治行妇产科手术患者368例，按就诊顺序编号分为对照组和观察组，每组184例。其中对照组于围手术期常规性应用抗生素，观察组则预防性应用抗生素，于术后比较两组的热退时间、最高体温、发病率、感染率、不良反应、抗生素人均使用量、药物费用及住院时间等指标。结果：术后，两组的热退时间比较差异无统计学意义（P0.05）；观察组的最高体温、发病率及感染率均低于对照组，比较差异有统计学意义（P0.05）；两组的术后不良反应发生率、抗生素人均使用量、药物费用及住院时间比较差异均具有统计学意义（P0.05）。结论：于妇产科围手术期预防性应用抗生素可有效预防疾病复发和感染，同时还可降低术后不良反应的发生率，缩短住院时间，减轻患者的经济负担。 　　关键词 妇产科 围手术期 抗生素 预防 　　Analysis of the preventive application of antibiotics in obstetrics and gynecology operation 　　Cheng Guilan 　　The Health Center of Taiping Town，Zhoucheng City，Shandong 273513 　　Abstract Objective：To explore the clinical effect of prophylactic application of antibiotics in obstetrics and gynecology operation.Methods：368 patients who were treated with obstetrics and gynecology operation were selected，they were divided into the control group and the observation group with 184 cases in each according to the order of treatment.The control group was treated by routine application of antibiotics in peri-operation period；the observation group was treated with the antibiotic application of antibiotics.After operation，some indicators of the two groups were compared，such as antipyretic time，the highest temperature，morbidity，infection rate，adverse reactions，the per capita amount of antibiotics，drug expense，the hospitalization time and so on.Results：After operation，the difference of antipyretic time between the two groups was not significant（P0.05）；in the observation group，the highest temperature，the incidence and infection rate were lower than the control group，the difference was statistically significant（P0.05）；the differences of postoperative incidence of adverse reactions，the per capita amount of antibiotics，drug expense and the hospitalization time between the two groups was statistically significant（P0.05）.Conclusion：The preventive application of antibiotics in obstetrics and gynecology operation can effectively prevent the recurrence of the di