探讨厄贝沙坦联合美托洛尔在高血压心脏病治疗中的应用.docVIP

探讨厄贝沙坦联合美托洛尔在高血压心脏病治疗中的应用 　　[摘要] 目的 分析厄贝沙坦联合美托洛尔在高血压心脏病治疗中的应用价值。方法 从该院2014年9月―2015年9月接收并治疗的高血压心脏病患者中随机选取62例并分为两组，对照组行厄贝沙坦治疗，观察组联合美托洛尔治疗，分析两组治疗前后舒张压、收缩压变化情况及治疗后临床效果。 结果 观察组治疗血压下降程度、心功能分级均优于对照组，比较差异有统计学的意义（P0.05）；且观察组治疗后总有效率93.55%，高于对照组总有效率77.42%（P0.05）。结论厄贝沙坦联合美托洛尔治疗高血压心脏病的效果显著，值得推广。 　　[关键词] 贝沙坦；联合；美托洛尔；高血压心脏病 　　[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742（2015）12（c）-0129-02 　　Study on the Application of Irbesartan Combined with Metoprolol in Treatment of Hypertensive Heart Disease 　　YANG Hua-zhi， WANG Dong-fang 　　Second department of cardiology， Chifeng Hospital of Inner Mongolia， 024000 China 　　[Abstract] Objective To analyze the application value of irbesartan combined with metoprolol in treatment of hypertensive heart disease. Methods 62 cases of patients with hypertensive heart disease admitted and treated in our hospital from September 2014 to September 2015 were selected and divided into two groups with 62 cases in each， the control group were treated with irbesartan， the observation group were treated with irbesartan combined with metoprolol， the changes of diastolic pressure and systolic pressure before and after treatment and the clinical effect after treatment of the two groups was analyzed. Results The decreased blood pressure level and cardiac functional grading in the observation group were better than those in the control group， and the comparison had statistical significance， （P0.05）；the total effective rate after treatment in the observation group was higher than that in the control group，（93.55% vs 77.42%），（P0.05）. Conclusion The effect of irbesartan combined with metoprolol in treatment of hypertensive heart disease is obvious， which is worth promotion. 　　[Key words] Irbesartan； Combined with； Metoprolol； Hypertensive heart disease 　　高血压心脏病是临床常见疾病，近年来随着我国人口老龄化的加剧，使得该病的患病率逐年上升。高血压心脏病的临床症状主要表现为四肢无力、头晕、头痛等，给患者的身心健康及生活质量造成严重影响。当前，临床上对于高血压心脏病的治疗是以厄贝沙坦为主，该药能够有效阻断血管紧张素II受体，但单纯采用该药治疗无法达到多重降压效果。因此，选择一种切实可行的治疗方法，改善高血压心脏病的预后是当前临床研究的重点[1]。该研究主要分析2014年9月―201