厄贝沙坦治疗持续性房颤疗效分析.docVIP

厄贝沙坦治疗持续性房颤疗效分析 　　【摘要】目的 分析探讨应用厄贝沙坦治疗持续性房颤的疗效，总结临床经验。方法 从我院2011年1月～2013年6月收治的持续性房颤患者当中选取58例作为研究对象，将这些患者随机分为对照组和观察组各29例。对照组患者给予常规抗凝治疗，观察组患者在常规抗凝治疗的基础上给予口服厄贝沙坦治疗，观察两组患者的疗效以及复发率。结果 观察组治疗总有效率、6个月和12个月的心率维持率、一年复发率等指标都显著优于对照组，差异具有统计学意义（P0.05）。两组治疗后左房径差异具有统计学意义（P0.05）。结论 在常规抗凝治疗基础上使用厄贝沙坦治疗持续性房颤，能够提高疗效，降低房颤复发率。 　　【关键词】厄贝沙坦；持续性房颤；疗效 　　【中图分类号】R541.5 【文献标识码】B 　　The clinical effect of irbesartan treatment of persistent atrial fibrillation 　　LU Cheng 　　（Department of internal medicine in Tongzhou District Fifth Peoples 　　Hospital， Jiangsu Nantong 226331， China） 　　【Abstract】Objective Analysis of the efficacy of irbesartan treatment of persistent， summarize clinical experience. Methods Select patients with persistent atrial fibrillation in our hospital in January 2011 to June 2013 period were studied. They were randomly divided into the control group and the observation group 29 cases. Implement conventional anticoagulant therapy in patients in the control group. Patients in the observation group while giving irbesartan conventional anticoagulation therapy. The clinical efficacy and the recurrence rate of the patients in two groups. Results Total effective observation group， the heart rate 6 months and maintain 12 months， one year recurrence rate and other indicators are significantly better than the control group， the difference is statistically significant （P0.05）. After treatment，The diameter of left atrial variation is very significant， highly statistically significant （P0.05）. Conclusion In conventional anticoagulation basis， Use of irbesartan treatment of persistent atrial fibrillation， can improve the therapeutic effect， reduce the rate of recurrence of atrial fibrillation.. 　　【Key words】Irbesartan； Persistent atrial fibrillation； Efficacy 　　房颤是心房颤动（atrial fibrillation；Af）的简称，是临床上最常见的心率失常症之一，几乎见于所有的器质性心脏病，非器质性心脏病也可发生，患有心血管疾病的患者易出现Af[1]。Af的病因比较复杂，致死率、致残率比较高，严重威胁患者的生命安全。目前，临床上治疗Af的主要方式是药物治疗，厄贝沙坦是其中的一种治疗药物，认为它对预防Af的发生以及控制Af进一步扩散方面具有显著的作用[2]。Af可分为持续性Af动、阵发性Af和永久性Af[3