材料物理专业氧化还原响应型中空介孔SiO2的制备及性能研究本科毕业设计论文.docx

本 科 毕 业 设 计（论文） 题 目：氧化还原响应型中空介孔SiO2的制备及性 能研究 学生姓名： 学 号： 专业班级：材料物理 指导教师： 2017年 6月18日 本科毕业设计(论文) 氧化还原响应型中空介孔SiO2的制备及性能研究 摘 要 氧化还原响应型的中空介孔二氧化硅（HMSS）具有空腔和介孔壳组成的分级结构，可用于高容量药物负载和控释。本文首先采用选择性蚀刻法制备HMSS并修饰氧化还原响应阀门；然后在HMSS内部负载缓蚀剂并用ZnO量子点封堵；采用扫描(SEM)和透射电子显微镜(TEM)、X射线衍射(XRD)、红外光谱(FT-IR)和热重分析（TGA）等表征HMSS的形貌和结构修饰；最后采用紫外光谱测定HMSS对缓蚀剂的响应释放规律。结果表明HMSS具有中空和介孔组成的分级结构，尺寸在300-400 nm；平均孔径和表面积分别为4.0 nm和894.26 m2·g-1；表面修饰的HMSS能够实现缓蚀剂的负载和氧化还原响应释放；随着二硫化物还原剂的量的增加，释放量和释放效率逐渐增加。本研究结果对填充智能纳米容器的功能涂层制备具有重要指导意义。 关键词：中空介孔二氧化硅；ZnO量子点；表面功能化；氧化还原响应；缓蚀剂负载和控释 Research of preparation and properties for redox-responsive hollow mesoporous silica Abstract Redox-responsive hollow mesoporous silica (HMSS) has a hierarchical mesoporous structure composed of a hollow cavity and mesoporous shell which is available for high capacity drug storage and controlled release. Firstly, HMSS was prepared by selective etching method and modified with the redox-responsive nanovalves. Next, the corrosion inhibitor was encapsulated in the HMSS and covered by ZnO quantum dots (QDs). Then, the morphology and structural functionalization of HMSS were characterized by scanning (SEM) and transition electron microscopy (TEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR) and thermogravimetric analysis (TGA). Finally, the responsive release of corrosion inhibitor was determined by UV spectroscopy. Obtained results reveal that the prepared HMSS exhibits an average size of 300-400 nm and has a hierarchical mesoporous structure composed of a hollow cavity and mesoporous shell. HMSS has an average pore size of 4.0 nm and a high surface area of 894.26 m2·g-1. The surface modification can achieve the successful loading and re-dox responsive releasing of corrosion inhibitor. In detail, the releasing efficiency gradually increased with the increase in the amount of the disulfide reducing agent. The results of this study are of great significance to the preparation of functional coatings filled with intellig