环糊精修饰的嵌段共聚物微胶囊制备及缓蚀剂的填装和释放性能研究毕业设计论文.docx

本 科 毕 业 设 计(论文) 题 目：环糊精修饰的嵌段共聚物微胶囊制备及缓蚀剂的填装和释放性能研究 学生姓名： 学 号： 专业班级：材料物理14-2班 指导教师： 中国石油大学（华东）本科生毕业（论文） 环糊精修饰的嵌段共聚物微胶囊制备及缓蚀剂的填装和释放性能研究 摘 要 随着防腐技术的不断提升，缓蚀剂受到了越来越多的运用。但是缓蚀剂普遍存在着易失效、具有污染性等缺点，所以如何控制缓蚀剂的释放以及使其在关键的时刻发挥作用是需要亟待解决的问题。本次毕设以β-环糊精为核心片段，利用ATRP的聚合方法，合成了一种pH响应型嵌段共聚物。借助环糊精特有的疏水性空腔通过主-客体相互作用包裹疏水性小分子缓蚀剂苯并三氮唑（BTA），并研究其在不同pH值下的释放率及释放时间。研究发现目标嵌段共聚物纳米组装体具有较好的载药率和包封率，同时可以有效地控制缓蚀剂的释放，赋予缓蚀剂pH值响应性和良好的水溶解性，这为后期将这种微胶囊加入到涂层中提供了一定的基础。 关键词：β-环糊精；嵌段共聚物；苯并三氮唑；缓慢释放；pH响应性 Preparation of Cyclodextrin-Modified Copolymer Microcapsules and Study on Filling and Releasing Performance of Corrosion Inhibitors Abstract With the continuous improvement of anti-corrosion technology, corrosion inhibitors have been used more and more. However, corrosion inhibitors generally have disadvantages such as easy to fail and pollution, so how to control the release of corrosion inhibitors and make them work at a critical moment is a problem that needs to be solved urgently. This time, I designed a pH-responsive block copolymer by using ATRP polymerization method with β-cyclodextrin as the core fragment. Hydrophobic small molecule inhibitor benzotriazole (BTA) was encapsulated by a host-guest interaction via a hydrophobic cavity specific to cyclodextrin, and its release rate and release time at different pH values were studied. The study found that the target block copolymer nano-assembly has better drug loading rate and encapsulation efficiency, and can effectively control the release of the corrosion inhibitor, and impart pH response and good water solubility to the inhibitor. This is Late addition of this microcapsule to the coating provides a certain basis. Keywords：β-cyclodextrin; block copolymer; hydrophobic Benzotriazole; sustained release; pH response  目 录 TOC \o 1-3 \h \z \u HYPERLINK \l _Toc515888266 第1章 绪论 1 HYPERLINK \l _Toc515888267 1.1 环糊精简介 1 HYPERLINK \l _Toc515888268 1.2 嵌段共聚物简介 1 HYPERLINK \l _Toc515888269 1.2.1 嵌段共聚物的制备方法以及环糊精聚合物的类型 1 HYPERLINK \l _Toc515888270 1.2.2 原子转移自由