多囊卵巢综合征不孕应用二甲双胍联合炔雌醇环丙孕酮治疗价值探析.docVIP

多囊卵巢综合征不孕应用二甲双胍联合炔雌醇环丙孕酮治疗价值探析 　　[摘要] 目的 探析多囊卵巢综合征不孕应用二甲双胍联合炔雌醇环丙孕酮治疗的价值。 方法 方便选取2014年5月―2016年4月?院收治的86例多囊卵巢综合征不孕患者作为观察目标，按照摸球法分为参照组（n=43）和试验组（n=43），参照组采用炔雌醇环丙孕酮治疗，试验组在参照组基础上联合二甲双胍治疗，观察并比较两组临床治疗效果。结果 试验组治疗后睾酮（1.4±0.1）nmol/L、胰岛素（8.6±3.5）mIU/L以及FSH（5.9±2.0）U/L、LH（6.3±1.4）U/L、LH/FSH（1.5±0.2）的改善效果优于参照组（1.5±0.2）nmol/L、（14.2±6.0）mIU/L、（5.1±1.9）U/L、（12.9±5.8）U/L、（2.5±0.1），组间差异有统计学意义（P0.05）；试验组排卵率88.4%、妊娠率69.8%与参照组53.5%、46.5%比较，组间差异有统计学意义（P0.05）；两组流产率比较，参照组高于试验组（P0.05）。结论 二甲双胍联合炔雌醇环丙孕酮治疗多囊卵巢综合征不孕效果肯定，有利于提高妊娠率和降低流产率，其可作为理想治疗方案在临床中积极推广使用。 　　[关键词] 多囊卵巢综合征；二甲双胍；炔雌醇环丙孕酮；不孕 　　[中图分类号] R711 [文献标识码] A [文章编号] 1674-0742（2017）02（a）-0110-03 　　[Abstract] Objective To study the value of melbine and Ethinylestradiol-cyproterone acetate in treatment of polycystic ovary syndrome. Methods Convenient selection 86 cases of patients with polycystic ovary syndrome admitted and treated in our hospital from May 2014 to April 2016 were selected as the research objects and divided into two groups with 43 cases in each， the control group were treated with ethinylestradiol-cyproterone acetate， while the test group were treated with melbine and ethinylestradiol-cyproterone acetate， and the clinical treatment effect of the two groups was observed and compared. Results After treatment， the improvement effect of testosterone， insulin， FSH， LH and LH/FSH in the test group was better than that in the control group[（1.4±0.1）nmol/L， （8.6±3.5）mIU/L， （5.9±2.0）U/L， （6.3±1.4）U/L， （1.5±0.2） vs （1.5±0.2）nmol/L，（14.2±6.0） mIU/L，（5.1±1.9） （U/L），（12.9±5.8）U/L， （2.5±0.1）]， and the differences between the two groups had statistical significance（P0.05）， and the differences in the ovulation rate and pregnancy rate between the test group and the control group had statistical significance（88.4%， 69.8% vs 53.5%，46.5%）（P0.05）， and the abortion rate in the control group was higher than that in the test group（P0.05）. Conclusion The effect of melbine and ethinylestradiol-cyproterone acetate in treatment of polycystic ovary s