T细胞进展TCR-MHC-2012幻灯片.pptVIP

* * * Green: anchor residues red: carboxyl termini blue: amino termini F: phenylalanine Y: tyrosine V: valin L: leucine I: isoleucine The upper and the lower panels show peptides that bind to two different alleles of MHC class I molecules respectively. Peptides also bind to MHC class I molecules through their amno (blue) and caboxyl termini. * The upper panel: a set of peptides that bind to the mouse MHC class II molecules AK allele. All contain the same core sequence but differ in length. The lower panel: different peptides binding to the human MHC class II allele HLA-DR3. The lengths of th